Intermittent antegrade warm versus cold blood cardioplegia: A prospective, randomized study

1994 ◽  
Vol 58 (1) ◽  
pp. 41-49 ◽  
Author(s):  
L.Conrad Pelletier ◽  
Michel Carrier ◽  
Yves Leclerc ◽  
Raymond Cartier ◽  
Eva Wesolowska ◽  
...  
Keyword(s):  
Randomized Study ◽  
Prospective Randomized Study ◽  
Blood Cardioplegia ◽  
Cold Blood ◽  
Cold Blood Cardioplegia

Continuous cold blood cardioplegia improves myocardial protection: a prospective randomized study

2004 ◽  
Vol 77 (2) ◽  
pp. 664-671 ◽  
Author(s):  
Yves A.G Louagie ◽  
Jacques Jamart ◽  
Manuel Gonzalez ◽  
Edith Collard ◽  
Serge Broka ◽  
...  
Keyword(s):  
Myocardial Protection ◽  
Randomized Study ◽  
Prospective Randomized Study ◽  
Blood Cardioplegia ◽  
Cold Blood ◽  
Cold Blood Cardioplegia

Intermittent Antegrade Tepid Versus Cold Blood Cardioplegia in Elective Myocardial Revascularization

1998 ◽  
Vol 65 (6) ◽  
pp. 1559-1565 ◽  
Author(s):  
Andrew C Fiore ◽  
Marc T Swartz ◽  
Robert Nevett ◽  
Paul J Vieth ◽  
Robert A Magrath ◽  
...  
Keyword(s):  
Myocardial Revascularization ◽  
Blood Cardioplegia ◽  
Cold Blood ◽  
Cold Blood Cardioplegia

The impact of del Nido cardioplegia solution on blood morphology parameters

Perfusion ◽  
2021 ◽  
pp. 026765912110490
Author(s):  
Krzysztof Sanetra ◽  
Wojciech Domaradzki ◽  
Marek Cisowski ◽  
Rajesh Shrestha ◽  
Krzysztof Białek ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Blood Cell ◽  
Valve Replacement ◽  
Transfusion Rate ◽  
Blood Cardioplegia ◽  
Blood Morphology ◽  
Cold Blood ◽  
Cold Blood Cardioplegia ◽  
Morphology Parameters

Background: Crystalloid cardioplegic solutions are believed to reduce hemoglobin significantly and increase the transfusion rate. However, recent reports indicate that the del Nido cardioplegia may preserve blood morphology parameters. Methods: In “The del Nido versus cold blood cardioplegia in aortic valve Replacement” trial patients undergoing aortic valve replacement were randomized into the del Nido (DN) or cold blood cardioplegia (CB) group. For the subanalysis, patients who underwent blood transfusions were excluded from the study. Red blood cell (RBC) count, hemoglobin, white blood cell (WBC) count and platelet (PLT) count were measured before the surgery, 24-, 48-, and 96 hours postoperatively. Furthermore, percental variation in first-last measure was compared in groups. In addition, indexed normalized ratio (INR) and activated partial thromboplastin time (aPTT) were compared preoperatively and 24 hours after the surgery. Results: Eighteen (24%) patients from the del Nido group and 22 (29.3%) patients from the CB group received blood product transfusions (p = 0.560) and were excluded from further analysis. As such, 57 patients remained in DN group and 53 patients remained in CB group. No difference was found in RBC, hemoglobin, WBC, and platelet count in time intervals. Percental variation in first-last measure revealed higher fall in RBC (p = 0.0024) and hemoglobin (p = 0.0028) in the CB group. No difference was shown in preoperative and 24-hour postoperative INR and aPTT. Conclusions: The del Nido cardioplegia does not decrease blood morphology parameters when compared to cold blood cardioplegia and may be used alternatively regardless of bleeding and coagulopathy risk.

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