Vitamin D3-induced calcium-binding protein: Partial purification, electrophoretic visualization, and tissue distribution

1967 ◽  
Vol 119 ◽  
pp. 536-540 ◽  
Author(s):  
A.N. Taylor ◽  
R.H. Wasserman
1971 ◽  
Vol 246 (9) ◽  
pp. 2808-2814 ◽  
Author(s):  
R.J. Ingersoll ◽  
R.H. Wasserman

1979 ◽  
Vol 236 (5) ◽  
pp. E556 ◽  
Author(s):  
J J Feher ◽  
R H Wasserman

The concentration of the vitamin D-induced calcium-binding protein (CaBP) and calcium absorption from the duodenum were investigated in chicks with an in vivo ligated-loop technique. The relation between CaBP and calcium absorption was dependent on a) source of vitamin D activity (either vitamin D3 or 1,25-dihydroxycholecalciferol); b) dosage of vitamin D3; c) time after administration of vitamin D3 to rachitic animals. To aid in the interpretation of these results, a phenomenological model was developed in which CaBP was viewed as being linearly related to a portion of calcium absorption. The model, when applied to the data, suggests that there is a "nonfunctional" pool of CaBP the size of which is determined by the vitamin D status of the animal. After correction for this nonfunctional pool, the proportionality between CaBP and calcium absorption is independent of the vitamin D status of the animal.


1971 ◽  
Vol 7 (1) ◽  
pp. 81-92 ◽  
Author(s):  
R. A. Corradino ◽  
J. G. Ebel ◽  
P. H. Craig ◽  
A. N. Taylor ◽  
R. H. Wasserman

1971 ◽  
Vol 7 (1) ◽  
pp. 93-102 ◽  
Author(s):  
R. A. Corradino ◽  
J. G. Ebel ◽  
P. H. Craig ◽  
A. N. Taylor ◽  
R. H. Wasserman

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