Effect of ethanol and other alcohols on the transport of amino acids and glucose by everted sacs of rat small intestine

1967 ◽  
Vol 135 (5) ◽  
pp. 1000-1007 ◽  
Author(s):  
Tsun Chang ◽  
Janie Lewis ◽  
A.J. Glazko
1978 ◽  
Vol 40 (2) ◽  
pp. 185-191 ◽  
Author(s):  
C. Shorrock ◽  
J. E. Ford

1. An extract containing ‘unavailable’ small peptides was isolated from an enzymic digest of heat-damaged cod fillet and examined for its influence on uptake of leucine in the rat small intestine, using the everted-sac technique.2. The extract strongly inhibited the uptake of leucine. It had no effect on uptake of glucose or its metabolism to lactate.3. The findings are discussed in relation to the concept (Buraczewski, Buraczewska & Ford, 1967) that the accumulation of ‘unavailable peptide’ material in the intestine, found in rats given heat-damaged protein, might hinder the absorption of amino acids by blocking a mechanism involved in their transport across the mucosal barrier.


1990 ◽  
Vol 10 (11) ◽  
pp. 1261-1271 ◽  
Author(s):  
Hillary J. Dowling ◽  
Esther G. Offenbacher ◽  
F. Xavier Pi-Sunyer

1975 ◽  
Vol 34 (2) ◽  
pp. 291-296 ◽  
Author(s):  
G. Raczyński ◽  
M. Snochowski ◽  
S. Buraczewski

1. A study was made of the metabolism of ɛ-(γ-L-glutamyl)-L[4, 5-3H]lysine (GL) in the rat.2. The compound was largely absorbed from the intestine and metabolized. Labelled lysine was incorporated into blood proteins.3. In an in vitro experiment with everted sacs of rat small intestine, GL passed through the intestinal wall unchanged.4. The results of comparative tests using homogenates of different body tissues indicated that the kidneys were particularly active in hydrolysing GL. Their activity was nine times greater than that of the liver and eighteen times greater than that of the small intestine.


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