Chloramphenicol inhibits hormone-dependent induction of cytoplasmic mRNA coding for the mitochondrial enzyme, carbamyl phosphate synthetase, in Rana catesbeiana tadpoles

1981 ◽  
Vol 654 (1) ◽  
pp. 67-76 ◽  
Author(s):  
Marcel Pouchelet ◽  
Gordon C. Shore
Keyword(s):  
Rana Catesbeiana ◽  
Mitochondrial Enzyme ◽  
Carbamyl Phosphate ◽  
Carbamyl Phosphate Synthetase

scholarly journals Biochemical Studies on Amphibian Metamorphosis

1960 ◽  
Vol 43 (4) ◽  
pp. 683-696 ◽  
Author(s):  
Woon Ki Paik ◽  
Philip P. Cohen
Keyword(s):  
Rana Catesbeiana ◽  
Morphological Changes ◽  
Biochemical Changes ◽  
Carbamyl Phosphate ◽  
Amphibian Metamorphosis ◽  
Carbamyl Phosphate Synthetase ◽  
Biochemical Studies ◽  
Stimulation Of

Thyroxine has been shown to accelerate the synthesis of carbamyl phosphate synthetase in the liver of Rana catesbeiana. Stimulation of carbamyl phosphate synthetase synthesis by thyroxine appears to be relatively specific because of the following observations: (1) succinoxidase activity decreased during the time that carbamyl phosphate synthetase increased; (2) liver catalase responded more slowly than carbamyl phosphate synthetase to thyroxine; (3) the ratio of biochemical changes/morphological changes was greatly altered during thyroxine-induced metamorphosis. The relationships between the concentration of thyroxine and (1) temperature; (2) duration of exposure of the tadpole to thyroxine; and (3) the activity of carbamyl phosphate synthetase during the induced synthesis of carbamyl phosphate synthetase by thyroxine are discussed. Chloramphenicol and thiouracil partly counteracted the effect of thyroxine on the synthesis of carbamyl phosphate synthetase.

scholarly journals Synthesis of Carbamyl Phosphate Synthetase in Amphibian Liver in Vitro

1969 ◽  
Vol 244 (19) ◽  
pp. 5295-5308 ◽  
Author(s):  
G.E. Shambaugh ◽  
J.B. Balinsky ◽  
Philip P. Cohen
Keyword(s):  
Carbamyl Phosphate ◽  
Carbamyl Phosphate Synthetase

scholarly journals Studies on the Mechanism of Action of Acetylglutamate as an Activator of Carbamyl Phosphate Synthetase

1964 ◽  
Vol 239 (6) ◽  
pp. 1935-1941 ◽  
Author(s):  
Leonard A. Fahien ◽  
James M. Schooler ◽  
Gregory A. Gehred ◽  
Philip P. Cohen
Keyword(s):  
Mechanism Of Action ◽  
Carbamyl Phosphate ◽  
Carbamyl Phosphate Synthetase
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