The stimulation of the phosphogluconate oxidation pathway by pyruvate under anaerobic conditions in diaphragm muscle and in rat brown adipose tissue

1962 ◽  
Vol 56 ◽  
pp. 153-155 ◽  
Author(s):  
Anne Beloff-Chain ◽  
Raffaella Catanzaro ◽  
E.B. Chain ◽  
L. Longinotti ◽  
Ines Masi ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Diaphragm Muscle ◽  
Anaerobic Conditions ◽  
Oxidation Pathway ◽  
Brown Adipose ◽  
Stimulation Of

Control of brown adipose tissue lipolysis and respiration by adenosine

1983 ◽  
Vol 245 (6) ◽  
pp. E555-E559 ◽  
Author(s):  
D. Szillat ◽  
L. J. Bukowiecki
Keyword(s):  
Adipose Tissue ◽  
Cyclic Amp ◽  
Palmitic Acid ◽  
Brown Adipose Tissue ◽  
Brown Adipocyte ◽  
Tissue Respiration ◽  
Dibutyryl Cyclic Amp ◽  
Response Curves ◽  
Brown Adipose ◽  
Stimulation Of

Adenosine competitively inhibited the stimulatory effects of (-)-isoproterenol on lipolysis and respiration in hamster brown adipocytes. The low value of the apparent ki for respiratory inhibition by adenosine (7 nM) indicated that the nucleoside may control brown adipocyte function under physiological concentrations. Significantly, the dose-response curves for isoproterenol stimulation of lipolysis and respiration were both shifted by adenosine to higher agonist concentrations by the same order of magnitude, providing additional evidence for a tight coupling between lipolysis and respiration. The inhibitory effects of adenosine were rapidly reversed by a) adenosine deaminase, b) agents known to increase intracellular cyclic AMP levels (isoproterenol, isobutylmethylxanthine, dibutyryl cyclic AMP), and c) direct stimulation of respiration with palmitic acid. These results, combined with the fact that adenosine failed to affect respiration evoked either by dibutyryl cyclic AMP or by palmitic acid, strongly indicate that adenosine regulates brown adipose tissue respiration at an early metabolic step of the stimulus-thermogenesis sequence, most probably at the level of the adenylate cyclase complex.

Stimulation of brown adipose tissue by polyphenols in extra virgin olive oil

2020 ◽  
pp. 1-8 ◽  
Author(s):  
L. Melguizo Rodríguez ◽  
R. Illescas-Montes ◽  
V. J. Costela-Ruiz ◽  
O. García-Martínez
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Olive Oil ◽  
Virgin Olive Oil ◽  
Extra Virgin Olive Oil ◽  
Brown Adipose ◽  
Stimulation Of

scholarly journals GDP binding to brown-adipose-tissue mitochondria of mice treated chronically with corticosterone

1983 ◽  
Vol 214 (1) ◽  
pp. 265-268 ◽  
Author(s):  
K S Galpin ◽  
R G Henderson ◽  
W P T James ◽  
P Trayhurn
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Cytochrome Oxidase ◽  
Oxidase Activity ◽  
Cytochrome Oxidase Activity ◽  
Acute Response ◽  
Brown Adipose ◽  
Brown Adipose Tissue Thermogenesis ◽  
Ad Libitum ◽  
Stimulation Of

Cytochrome oxidase activity and mitochondrial GDP binding were decreased in brown adipose tissue of mice treated chronically with corticosterone. These changes occurred both in corticosterone-treated mice fed ad libitum and in treated mice pair-fed to control animals. Although the dietary stimulation of brown-adipose-tissue thermogenesis was suppressed by corticosterone, the acute response to cold was not affected.

scholarly journals Differences in Sympathetic Nervous Stimulation of Brown Adipose Tissue Between the Young and Old, and the Lean and Obese

2015 ◽  
Vol 57 (3) ◽  
pp. 372-377 ◽  
Author(s):  
L. Bahler ◽  
H. J. Verberne ◽  
W. M. Admiraal ◽  
W. J. Stok ◽  
M. R. Soeters ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Nervous Stimulation ◽  
Brown Adipose ◽  
Sympathetic Nervous ◽  
Stimulation Of
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