5-HT1A and benzodiazepine receptors in the basolateral amygdala modulate anxiety in the social interaction test, but not in the elevated plus-maze

1996 ◽  
Vol 732 (1-2) ◽  
pp. 145-153 ◽  
Author(s):  
Luis E. Gonzalez ◽  
Nick Andrews ◽  
Sandra E. File
Keyword(s):  
Social Interaction ◽  
Basolateral Amygdala ◽  
Elevated Plus Maze ◽  
Benzodiazepine Receptors ◽  
Social Interaction Test ◽  
Plus Maze ◽  
The Social ◽  
Interaction Test

Tianeptine counteracts the anxiogenic effects of benzodiazepine withdrawal, but not those of exposure to cat odour

1993 ◽  
Vol 8 (S2) ◽  
pp. 75s-80s
Author(s):  
SE File ◽  
N Andrews ◽  
H Zangrossi
Keyword(s):  
Social Interaction ◽  
Acute Administration ◽  
Social Interaction Test ◽  
Anxiety States ◽  
Plus Maze ◽  
The Social ◽  
5 Ht Uptake ◽  
Benzodiazepine Withdrawal ◽  
Chronic Diazepam ◽  
Interaction Test

SummaryTianeptine is a clinically effective anti-depressant with the unusual profile of increasing 5-HT uptake, thereby decreasing the synaptic availability of 5-HT. In the social interaction test of anxiety in the rat, withdrawal from chronic diazepam treatment produced a significant anxiogenic response that was reversed by acute administration of tianeptine (2.5–10 mg/kg). These doses were without significant effect in the vehicle-treated rats. Exposure of rats to cat odour resulted in anxiogenic responses in the plus-maze and social interaction tests and in decreased exploration. These changes were not reversed by 5 days treatment with tianeptine (2.5–10 mg/kg). Thus, tianeptine may not he effective in all anxiety states, but could be particularly useful in treating patients withdrawn from benzodiazepines.

scholarly journals Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test

2013 ◽  
Vol 41 ◽  
pp. 30-35 ◽  
Author(s):  
Valéria Almeida ◽  
Raquel Levin ◽  
Fernanda Fiel Peres ◽  
Suzy T. Niigaki ◽  
Mariana B. Calzavara ◽  
...  
Keyword(s):  
Social Interaction ◽  
Social Interaction Test ◽  
The Social ◽  
Interaction Test

Anxiogenic activity of quinolinic acid and kynurenine in the social interaction test in mice

1996 ◽  
Vol 10 (3) ◽  
pp. 246-249 ◽  
Author(s):  
Izyaslav P. Lapin ◽  
Ludmila G. Mutovkina ◽  
Ivan V. Ryzov ◽  
Said Mirzaev
Keyword(s):  
Social Interaction ◽  
Quinolinic Acid ◽  
Social Interaction Test ◽  
The Social ◽  
Interaction Test
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