Stimulation of human lymphocytes with irradiated cells of the autologous Epstein-Barr virus-transformed cell line

1982 ◽  
Vol 67 (1) ◽  
pp. 129-140 ◽  
Author(s):  
L.E. Wallace ◽  
A.B. Rickinson ◽  
M. Rowe ◽  
D.J. Moss ◽  
D.J. Allen ◽  
...  
Keyword(s):  
Cell Line ◽  
Epstein Barr Virus ◽  
Human Lymphocytes ◽  
Transformed Cell ◽  
Barr Virus ◽  
Transformed Cell Line ◽  
Epstein Barr ◽  
Stimulation Of

Stimulation of human lymphocytes with irradiated cells of the autologous Epstein-Barr virus-transformed cell line

1982 ◽  
Vol 67 (1) ◽  
pp. 141-151 ◽  
Author(s):  
D.J. Allen ◽  
A.B. Rickinson ◽  
L.E. Wallace ◽  
M. Rowe ◽  
D.J. Moss ◽  
...  
Keyword(s):  
Cell Line ◽  
Epstein Barr Virus ◽  
Human Lymphocytes ◽  
Transformed Cell ◽  
Barr Virus ◽  
Transformed Cell Line ◽  
Epstein Barr ◽  
Stimulation Of

scholarly journals Epstein-Barr virus RNA. V. Viral RNA in a restringently infected, growth-transformed cell line.

1980 ◽  
Vol 36 (2) ◽  
pp. 506-518 ◽  
Author(s):  
W King ◽  
A L Thomas-Powell ◽  
N Raab-Traub ◽  
M Hawke ◽  
E Kieff
Keyword(s):  
Cell Line ◽  
Epstein Barr Virus ◽  
Viral Rna ◽  
Transformed Cell ◽  
Barr Virus ◽  
Transformed Cell Line ◽  
Virus Rna ◽  
Epstein Barr

scholarly journals Establishment and characterization of an Epstein-Barr virus transformed cell line with strong phagocytic activity

Blood ◽  
1989 ◽  
Vol 74 (1) ◽  
pp. 430-436 ◽  
Author(s):  
P von den Driesch ◽  
R Bhardwaj ◽  
HD Flad ◽  
DC Neugebauer ◽  
HJ Pielken ◽  
...  
Keyword(s):  
Cell Line ◽  
Phagocytic Activity ◽  
Antigen Processing ◽  
Epstein Barr Virus ◽  
Interleukin 1 ◽  
Immunoglobulin M ◽  
Nuclear Antigen ◽  
Barr Virus ◽  
Transformed Cell Line ◽  
Epstein Barr

Abstract An immunoglobulin M (IgM)-positive cell line, Ms 28, apparently spontaneously transformed by Epstein-Barr virus (EBV) was established from peripheral blood cells of a patient with immature myeloblastic leukemia. It has been characterized according to phenotype, cytochemistry, and membrane antigen pattern. The cell line expresses lymphoid markers like CD 19, CD 22, and CD 30 and synthesizes and secretes IgM. Monocyte markers CD 11c, CD 14, and CD 15 are absent. Neither interleukin-1 (IL-1), nor tumor necrosis factor (TNF-alpha) are produced. But Ms 28 cells show strong phagocytic activity and engulf Latex particles and sheep RBCs (SRBCs) that need not to be opsonized. The phagocytic activity can be inhibited by chloroquine. Both phagocytosis and EBV nuclear-antigen (EBNA) expression can be observed in one and the same cell. Ms 28 cells might be useful to study immunologic activities like antigen processing and presentation.

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