The biological fate in rats of vinyl chloride in relation to its oncogenicity

1975 ◽  
Vol 11 (6) ◽  
pp. 545-562 ◽  
Author(s):  
T. Green ◽  
D.E. Hathway
Keyword(s):  
Vinyl Chloride ◽  
Biological Fate

Certain candidate genes polymorphic variants impact in the development of hypertension when exposed to vinyl chloride

2020 ◽  
pp. 667-667
Author(s):  
I. V. Kudaeva ◽  
O. A. Dyakovich ◽  
I. M. Eshchina
Keyword(s):  
Candidate Genes ◽  
Vinyl Chloride ◽  
Polymorphic Variant ◽  
Apo E ◽  
Genotype C ◽  
Polymorphic Variants

It was found that in persons exposed by vinyl chloride, the risk of hypertension increases six times in carriers of the genotype C/C polymorphic variant of Leu28Pro gene APO E, 9.5 times - in carriers of the genotype T/T polymorphic variant C786T gene eNOS3 and 1.75 times - in carriers of the genotype T/C polymorphic variant Met 235 Thr gene AGT.

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