A multicentred phase III comparative clinical trial of depot-medroxyprogesterone acetate given three-monthly at doses of 100mg or 150mg: 1. Contraceptive efficacy and side effects

Contraception ◽  
1986 ◽  
Vol 34 (3) ◽  
pp. 223-235 ◽  
Author(s):  
S. Said ◽  
K. Omar ◽  
Suporn Koetsawang ◽  
Orawan Kiriwat ◽  
Yuwadee Srisatayapan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Side Effects ◽  
Medroxyprogesterone Acetate ◽  
Phase Iii ◽  
Contraceptive Efficacy ◽  
Comparative Clinical Trial ◽  
Depot Medroxyprogesterone Acetate

A Double-Blind Comparative Clinical Trial of Floctafenine and Four Other Analgesics Conducted in General Practice

1976 ◽  
Vol 4 (3) ◽  
pp. 179-182 ◽  
Author(s):  
D M Lomas ◽  
J Gay ◽  
R N Midha ◽  
D L Postlethwaite
Keyword(s):  
Clinical Trial ◽  
General Practice ◽  
Side Effects ◽  
Analgesic Effect ◽  
Rank Order ◽  
Controlled Trial ◽  
The Other ◽  
Double Blind ◽  
Comparative Clinical Trial

Three hundred and twelve patients suffering from painful conditions were admitted to a multicentre, double-blind controlled trial, conducted in general practice in which five analgesics—floctafenine (Idarac), paracetamol, aspirin, dihydrocodeine and pentazocine—were compared. Overall ratings of analgesic effect placed floctafenine first in rank order. Floctafenine was statistically significantly superior in effect to pentazocine but not to the other three agents as far as doctor ratings were concerned; and superior to both pentazocine and dihydrocodeine in the opinion of patients. Fewer patients experienced side-effects on floctafenine than on the other four analgesics and this difference between floctafenine and pentazocine, and floctafenine and dihydrocodeine was statistically significant.

A Comparative Clinical Trial of Org GB 94 and Imipramine in the Treatment of Depression in General Practice

1975 ◽  
Vol 3 (4) ◽  
pp. 251-260 ◽  
Author(s):  
J E Murphy
Keyword(s):  
Clinical Trial ◽  
General Practice ◽  
Side Effects ◽  
Treatment Period ◽  
Therapeutic Effect ◽  
Double Blind ◽  
Comparative Clinical Trial ◽  
Two Agents ◽  
Treatment Of Depression

A double-blind controlled comparative clinical trial of Org GB 94 and imipramine was conducted in general practice. Fifty-five patients were treated with Org GB 94 (60 mg daily) and fifty-four with imipramine (150 mg daily). In the doses employed both agents were equally effective in relieving depression over a four week treatment period. Tolerance of the two agents was similar. Although no statistically significant differences emerged, with regard to both therapeutic effect and some side-effects a trend in favour of Org GB 94 was apparent.

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