Ablation of the olfactory bulb up-regulates the rate of neurogenesis and induces precocious cell death in olfactory epithelium

1992 ◽  
Vol 115 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Virginia McM. Carr ◽  
Albert I. Farbman
Keyword(s):  
Cell Death ◽  
Olfactory Bulb ◽  
Olfactory Epithelium

scholarly journals Extinction reverses olfactory fear-conditioned increases in neuron number and glomerular size

2015 ◽  
Vol 112 (41) ◽  
pp. 12846-12851 ◽  
Author(s):  
Filomene G. Morrison ◽  
Brian G. Dias ◽  
Kerry J. Ressler
Keyword(s):  
Olfactory Bulb ◽  
Learning And Memory ◽  
Olfactory Epithelium ◽  
Olfactory System ◽  
Structural Changes ◽  
Freezing Behavior ◽  
Extinction Training ◽  
Odor Stimulus ◽  
Main Olfactory Epithelium ◽  
Odor Learning

Although much work has investigated the contribution of brain regions such as the amygdala, hippocampus, and prefrontal cortex to the processing of fear learning and memory, fewer studies have examined the role of sensory systems, in particular the olfactory system, in the detection and perception of cues involved in learning and memory. The primary sensory receptive field maps of the olfactory system are exquisitely organized and respond dynamically to cues in the environment, remaining plastic from development through adulthood. We have previously demonstrated that olfactory fear conditioning leads to increased odorant-specific receptor representation in the main olfactory epithelium and in glomeruli within the olfactory bulb. We now demonstrate that olfactory extinction training specific to the conditioned odor stimulus reverses the conditioning-associated freezing behavior and odor learning-induced structural changes in the olfactory epithelium and olfactory bulb in an odorant ligand-specific manner. These data suggest that learning-induced freezing behavior, structural alterations, and enhanced neural sensory representation can be reversed in adult mice following extinction training.

Colchicine-induced cell death and proliferation in the olfactory epithelium and vomeronasal organ of the mouse

1998 ◽  
Vol 198 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Y. Suzuki ◽  
Masako Takeda ◽  
Nobuko Obara ◽  
Noriyo Suzuki
Keyword(s):  
Cell Death ◽  
Olfactory Epithelium ◽  
Vomeronasal Organ

BDNF expression in olfactory bulb and epithelium during regeneration of olfactory epithelium

2012 ◽  
Vol 516 (1) ◽  
pp. 45-49 ◽  
Author(s):  
Atsuhiro Uranagase ◽  
Sayaka Katsunuma ◽  
Kiyoshi Doi ◽  
Ken-Ichi Nibu
Keyword(s):  
Olfactory Bulb ◽  
Olfactory Epithelium ◽  
Bdnf Expression
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