Effects of insulin and glucagon on amino acid transport into the liver and opercular muscle of the eel in vitro

1983 ◽  
Vol 51 (2) ◽  
pp. 213-218 ◽  
Author(s):  
Yasuo Inui ◽  
Hiroko Ishioka
1961 ◽  
Vol 200 (4) ◽  
pp. 675-678 ◽  
Author(s):  
J. L. Kostyo ◽  
J. E. Schmidt

Hypophysectomized rat diaphragms, which were immersed briefly in dilute solutions of growth hormone and then washed thoroughly, subsequently transported α-aminoisobutyric acid-1-C14 at a greater rate than the controls. Growth hormones of bovine, porcine, simian and human origins were all effective. Increasing either the hormone concentration or the length of time that the diaphragms were immersed in growth hormone solutions increased the effect on amino acid transport. Prolonged washing of the diaphragms following exposure to growth hormone did not reduce the magnitude of the effect on amino acid transport. Moreover, reducing the temperature of the growth hormone solutions did not diminish the resultant effect on amino acid transport. From these results, it was concluded that the initial interaction between growth hormone and rat muscle in vitro occurs rapidly and the modification produced by this interaction is relatively stable.


Glia ◽  
2011 ◽  
Vol 59 (11) ◽  
pp. 1684-1694 ◽  
Author(s):  
Melissa S. Pathmajeyan ◽  
Sarjubhai A. Patel ◽  
James A. Carroll ◽  
Todd Seib ◽  
James F. Striebel ◽  
...  

1969 ◽  
Vol 16 (4) ◽  
pp. 577-585 ◽  
Author(s):  
A. V. Lorenzo ◽  
R. W. P. Cutler

1984 ◽  
Vol 27 (1) ◽  
pp. 63-72 ◽  
Author(s):  
Randall B. Newton ◽  
Jerome L. Sullivan ◽  
A. Gib Debusk

1975 ◽  
Vol 229 (2) ◽  
pp. 518-523 ◽  
Author(s):  
JJ Hajjar ◽  
RN Khuri ◽  
AB Bikhazi

The effect of bile salts on alanine absorption across four regional sites of rabbit intestine was examined using an in vivo single-pass perfusion technique. Na-deoxycholate at a concentration of 3 mM reduced alanine absorption across all levels of the intestine, and a higher concentration (10 mM) of Na-taurodeoxycholate (TDC) caused only a minimal reduction of alanine absorption in the jejunum. TDC, however, was more effective in in vitro experiments, causing an incrase in transmural serosal-to-mucosal flux of alanine and phenylalanine, particularly when present in both the mucosal and serosal media. It also reduced the mucosal-to-serosal alanine flux rate when present only in the mucosal medium. The influx of these amino acids across the mucosal brush border membrane was also decreased by TDC. These amino acid transport changes correlated fairly well with some observed histological changes of the intestinal epithelium. This suggests that bile salt inhibition of amino acid absorption is nonspecific in type and can be mainly explained as being the result of an injurious action of these surface-active agents on the rabbit intestine.


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