The Impact of Re-Mating Interval and Genotype on Physiological Response of Rabbits after First Kindling

This is an experiment aimed to study the effect of re-mating interval on rabbit does after first kindling on hormonal (insulin, leptin, and T3) and metabolites (triglycerides, urea, and glucose) levels. DNA damage in ovary cells of rabbit does during the 2nd parity was also studied. Two varieties were used: APRI (synthetic line) and Baladi Black (BB, Egyptian breed). A total number of 120 mature rabbit does (60 does for each breed) were 6 months of age and were used at the beginning of the breeding season. Does of each breed were divided into three equal groups according to reproductive rhythm. The 1st group was postpartum (PP). The 2nd group was 11 days after parturition (P11). The 3rd group was post-weaning (PW). There were significant (P≥0.05) differences in plasma leptin concentration during 1st parity. The highest value of plasma leptin concentration was recorded by the PW group at mating. Also, there were significant differences in plasma insulin and T3 hormones concentrations of doe rabbits. The highest value of plasma insulin concentration was recorded by the PW group at mating in 1st parity and the highest value of plasma T3 hormone concentration was recorded for the PS group at mating. While there were insignificant differences during 2nd parity in T3 hormone concentration in rabbits, the differences of plasma glucose and triglyceride concentrations of doe rabbits during 1st parity and 2nd parity were significant. However, the highest significant value of plasma glucose concentration was recorded by the PW group at mating. On the other hand, there were insignificant differences in plasma urea concentration of doe rabbits during 1st parity and 2nd parity. Finally, no significant effects were observed on comet length, head diameter, tail length, or DNA % tail.

Body Composition and Its Impact on the Hormonal Disturbances in Women with Polycystic Ovary Syndrome

We investigated the relationship between selected body composition (BC) parameters and included 55 women diagnosed with PCOS and 29 women in which PCOS was excluded. Hormone concentration and BC parameters were assessed during hospitalization. Women with PCOS had higher concentration of luteinizing hormones, total testosterone, androstenedione, and Anti-Müllerian hormones compared to women that were not diagnosed with PCOS. We did not observe any significant differences in the BC parameters between both groups as well as between four PCOS phenotype subgroups. Only in the group of women with PCOS was the concentration of sex hormone binding globulin and free testosterone correlated with all investigated BC parameters. Correspondence analysis did not confirm unambiguously associations between phenotypes of PCOS and the value of BC parameters, while logistic regression revealed that increased Anti-Müllerian hormone concentration and the value of body mass index could be useful parameters in differentiating women with PCOS and women with other disorders. The ROC analysis performed on the entire group of women also confirmed that the concentration of Anti-Müllerian hormones could be a powerful parameter to categorize women as suffering from PCOS.

PERKECAMBAHAN BENIH KOPI (Coffea sp) DENGAN PEMBERIAN KONSENTRASI HORMON GIBERELLIN (GA3) DAN JENIS AIR YANG BERBEDA

<p><em>West Sumatra is one producing coffee area in Indonesia a significant contribution to economy in Indonesian, because production coffee in West Sumatra unstable, it is necessary to expand the area. The propagation plants coffee is carried out in generative manner and needs be optimized with treating gibberellin hormone and water temperature to germination stage of coffee seeds.</em><em>Th</em><em>e </em><em>research</em><em> </em><em>conducted at the Seed Technology Laboratory</em><em> </em><em>Faculty</em><em> </em><em>A</em><em>g</em><em>iculture, Andalas University from</em><em> Mei</em><em> to</em><em> Agust</em><em> 202</em><em>1</em><em>.</em><em> </em><em>Measurement parameters were germination rate (days), normal germination (%), abnormal germination (%) and dead seeds (%). </em><em>The results of observations of germination rate (days), normal germination (%) and abnormal germination (%) showed a significant effect. While the data had no significant effect on the observation of dead seeds (%) in the treatment of gibberellin hormone concentration and treatment of water types, which in the observation of normal sprouts was the highest, namely in the treatment of 400 ppm gibberellin hormone concentration with coconut water (G4J3) of 86.67% and on seed observation. The highest death rate was treatment (G1J2), which was 33.33%. </em></p>

Role of Hydrogen Sulfide in the Endocrine System

Hydrogen sulfide (H2S), as one of the three known gaseous signal transduction molecules in organisms, has attracted a surging amount of attention. H2S is involved in a variety of physiological and pathological processes in the body, such as dilating blood vessels (regulating blood pressure), protecting tissue from ischemia-reperfusion injury, anti-inflammation, carcinogenesis, or inhibition of cancer, as well as acting on the hypothalamus and pancreas to regulate hormonal metabolism. The change of H2S concentration is related to a variety of endocrine disorders, and the change of hormone concentration also affects the synthesis of H2S. Understanding the effect of biosynthesis and the concentration of H2S on the endocrine system is useful to develop drugs for the treatment of hypertension, diabetes, and other diseases.