Presence of d-amino-acid oxidase protein in mutant mice lacking d-amino-acid oxidase activity

1991 ◽  
Vol 23 (11) ◽  
pp. 1301-1305 ◽  
Author(s):  
Konno Ryuichi ◽  
Yamamoto Katsuhiko ◽  
Niwa Akira ◽  
Yasumura Yosihiro
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Mutant Mice ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Determination of Free -Proline and -Leucine in the Brains of Mutant Mice Lacking -Amino Acid Oxidase Activity

2001 ◽  
Vol 298 (2) ◽  
pp. 253-258 ◽  
Author(s):  
Kenji Hamase ◽  
Tomomi Inoue ◽  
Akiko Morikawa ◽  
Ryuichi Konno ◽  
Kiyoshi Zaitsu
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Mutant Mice ◽  
Acid Oxidase ◽  
Free Proline ◽  
Amino Acid Oxidase

Excessive urinary excretion of methionine in mutant mice lacking d-amino-acid oxidase activity

Metabolism ◽  
1988 ◽  
Vol 37 (12) ◽  
pp. 1139-1142 ◽  
Author(s):  
Ryuichi Konno ◽  
Kazumasa Isobe ◽  
Akira Niwa ◽  
Yosihiro Yasumura
Keyword(s):  
Amino Acid ◽  
Urinary Excretion ◽  
Oxidase Activity ◽  
Mutant Mice ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Presence and origin of large amounts of d-proline in the urine of mutant mice lacking d-amino acid oxidase activity

2006 ◽  
Vol 386 (3) ◽  
pp. 705-711 ◽  
Author(s):  
Kenji Hamase ◽  
Sayaka Takagi ◽  
Akiko Morikawa ◽  
Ryuichi Konno ◽  
Akira Niwa ◽  
...  
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Mutant Mice ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

d-Aminoaciduria in mutant mice lackingd-amino-acid oxidase activity

Amino Acids ◽  
1991 ◽  
Vol 1 (2) ◽  
pp. 239-246 ◽  
Author(s):  
R. Konno ◽  
M. Ikeda ◽  
A. Niwa ◽  
Y. Yasumura
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Mutant Mice ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Behaviors of Mutant Mice Lacking d-Amino-Acid Oxidase Activity

D-Amino Acids ◽  
2016 ◽  
pp. 51-64 ◽  
Author(s):  
Hiroaki Sakaue ◽  
Hiroko Ohide ◽  
Masahiro Yamanaka ◽  
Ryuichi Konno
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Mutant Mice ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Variations of l- and d-amino acid levels in the brain of wild-type and mutant mice lacking d-amino acid oxidase activity

2018 ◽  
Vol 410 (12) ◽  
pp. 2971-2979 ◽  
Author(s):  
Siqi Du ◽  
Yadi Wang ◽  
Choyce A. Weatherly ◽  
Kylie Holden ◽  
Daniel W. Armstrong
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Mutant Mice ◽  
Acid Oxidase ◽  
Wild Type ◽  
Amino Acid Oxidase ◽  
Amino Acid Levels ◽  
The Brain

Impairment of Platelet Aggregation by Echis colorata Venom Mediated by L-Amino Acid Oxidase or H2O2

1982 ◽  
Vol 48 (03) ◽  
pp. 277-282 ◽  
Author(s):  
I Nathan ◽  
A Dvilansky ◽  
T Yirmiyahu ◽  
M Aharon ◽  
A Livne
Keyword(s):  
Hydrogen Peroxide ◽  
Amino Acid ◽  
Platelet Aggregation ◽  
Snake Venom ◽  
Oxidase Activity ◽  
Enzyme Preparation ◽  
Acid Oxidase ◽  
Crude Venom ◽  
Amino Acid Oxidase ◽  
Hemostatic Disorders

SummaryEchis colorata bites cause impairment of platelet aggregation and hemostatic disorders. The mechanism by which the snake venom inhibits platelet aggregation was studied. Upon fractionation, aggregation impairment activity and L-amino acid oxidase activity were similarly separated from the crude venom, unlike other venom enzymes. Preparations of L-amino acid oxidase from E.colorata and from Crotalus adamanteus replaced effectively the crude E.colorata venom in impairment of platelet aggregation. Furthermore, different treatments known to inhibit L-amino acid oxidase reduced in parallel the oxidase activity and the impairment potency of both the venom and the enzyme preparation. H2O2 mimicked characteristically the impairment effects of L-amino acid oxidase and the venom. Catalase completely abolished the impairment effects of the enzyme and the venom. It is concluded that hydrogen peroxide formed by the venom L-amino acid oxidase plays a role in affecting platelet aggregation and thus could contribute to the extended bleeding typical to persons bitten by E.colorata.

The Effect of Castration and Testosterone Propionate on d-Amino Acid Oxidase Activity in the Mouse

Science ◽  
1943 ◽  
Vol 98 (2534) ◽  
pp. 89-89
Author(s):  
L. C. Clark ◽  
C. D. Kochakian ◽  
R. Phyllis Fox
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Testosterone Propionate ◽  
Acid Oxidase ◽  
Amino Acid Oxidase
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