In vitro pulsatile flow velocity and shear stress measurements in the vicinity of mechanical mitral heart valve prostheses

1986 ◽  
Vol 19 (1) ◽  
pp. 39-51 ◽  
Author(s):  
Yi-Ren Woo ◽  
Ajit P. Yoganathan
1992 ◽  
Vol 15 (11) ◽  
pp. 681-685 ◽  
Author(s):  
M.O. Wendt ◽  
M. Pohl ◽  
S. Pratsch ◽  
D. Lerche

Hemolytic and subhemolytic blood damage by mechanical heart valve prostheses have been observed in both clinical and in vitro investigations. A direct comparison between these studies is not possible. Nevertheless the transfer of some in vitro results to the behaviour of the valve in situ may be performed considering the similarity principle. This requires the use of dimensionless similarity numbers such as the plasma's hemoglobin concentration (PHb) or others, instead of dimensioned parameters. To evaluate the in vitro hemolysis of valve prosthesis a test chamber filled with human banked blood was used. An artificial ventricle ensuring an oscillatory flow through the valve was also used. The rise of PHb was evaluated in terms of a similarity number, called the lysis number. This number describes the probability of destroying a single red blood cell participating once in the hemolytic process under consideration. The lysis number, a Björk-Shiley valve (TAD 29), was found to be in the order of 2 × 10−4. From this, the survival time of erythrocytes in patients with an artificial heart valve was estimated. It was found to be in the order of 20 d of T50 Cr in agreement with clinical results


1993 ◽  
Vol 7 (2) ◽  
pp. 107-108
Author(s):  
J VANSON ◽  
H REUL ◽  
U STEINSEIFER ◽  
B SCHMITZ ◽  
A SCHMID ◽  
...  

1988 ◽  
Vol 96 (6) ◽  
pp. 952-961 ◽  
Author(s):  
Erwin Knott ◽  
Helmut Reul ◽  
Martin Knoch ◽  
Ulrich Steinseifer ◽  
Günter Rau

2014 ◽  
Vol 41 (1) ◽  
pp. 74-82 ◽  
Author(s):  
Maria-Benedicta Edwards ◽  
John Mclean ◽  
Stephanos Solomonidis ◽  
Barrie Condon ◽  
Terence Gourlay

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