Interactions between large organic ions of opposite charge

1977 ◽  
Vol 59 (2) ◽  
pp. 350-359 ◽  
Author(s):  
G.I Mukhayer ◽  
S.S Davis
Keyword(s):  
Opposite Charge ◽  
Organic Ions

Interactions between large organic ions of opposite charge

1977 ◽  
Vol 61 (3) ◽  
pp. 582-589 ◽  
Author(s):  
G.I. Mukhayer ◽  
S.S. Davis
Keyword(s):  
Opposite Charge ◽  
Organic Ions

scholarly journals Structural basis of adhesive binding by desmocollins and desmogleins

2016 ◽  
Vol 113 (26) ◽  
pp. 7160-7165 ◽  
Author(s):  
Oliver J. Harrison ◽  
Julia Brasch ◽  
Gorka Lasso ◽  
Phinikoula S. Katsamba ◽  
Goran Ahlsen ◽  
...  
Keyword(s):  
Amino Acids ◽  
Crystal Structures ◽  
Structural Basis ◽  
Cellular Interactions ◽  
Opposite Charge ◽  
Charged Amino Acids ◽  
Structural Framework ◽  
Classical Cadherins ◽  
Coated Bead

Desmosomes are intercellular adhesive junctions that impart strength to vertebrate tissues. Their dense, ordered intercellular attachments are formed by desmogleins (Dsgs) and desmocollins (Dscs), but the nature of trans-cellular interactions between these specialized cadherins is unclear. Here, using solution biophysics and coated-bead aggregation experiments, we demonstrate family-wise heterophilic specificity: All Dsgs form adhesive dimers with all Dscs, with affinities characteristic of each Dsg:Dsc pair. Crystal structures of ectodomains from Dsg2 and Dsg3 and from Dsc1 and Dsc2 show binding through a strand-swap mechanism similar to that of homophilic classical cadherins. However, conserved charged amino acids inhibit Dsg:Dsg and Dsc:Dsc interactions by same-charge repulsion and promote heterophilic Dsg:Dsc interactions through opposite-charge attraction. These findings show that Dsg:Dsc heterodimers represent the fundamental adhesive unit of desmosomes and provide a structural framework for understanding desmosome assembly.

scholarly journals Particle size distribution of inorganic and organic ions in coastal and inland Antarctic aerosol

2016 ◽  
Vol 24 (3) ◽  
pp. 2724-2733 ◽  
Author(s):  
Elena Barbaro ◽  
Sara Padoan ◽  
Torben Kirchgeorg ◽  
Roberta Zangrando ◽  
Giuseppa Toscano ◽  
...  
Keyword(s):  
Particle Size ◽  
Particle Size Distribution ◽  
Size Distribution ◽  
Organic Ions ◽  
Inorganic And Organic
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