Comparison of the effects of amino acid mixture and placebo on plasma tryptophan to large neutral amino acid ratio

Life Sciences ◽  
1995 ◽  
Vol 56 (17) ◽  
pp. 1395-1400 ◽  
Author(s):  
Barbara E. Wolfe ◽  
Eran D. Metzger ◽  
David C. Jimerson
Keyword(s):  
Amino Acid ◽  
Amino Acid Mixture ◽  
Neutral Amino Acid ◽  
Acid Mixture ◽  
Large Neutral Amino Acid ◽  
Plasma Tryptophan ◽  
Acid Ratio

scholarly journals Exercise but Not Supplemental Dietary Tryptophan Influences Heart Rate and Respiratory Rate in Sled Dogs

2020 ◽  
Vol 7 (3) ◽  
pp. 97 ◽  
Author(s):  
Emma Thornton ◽  
James R. Templeman ◽  
Michael Bower ◽  
John P. Cant ◽  
Graham P. Holloway ◽  
...  
Keyword(s):  
Heart Rate ◽  
Amino Acid ◽  
Respiratory Rate ◽  
Control Diet ◽  
Neutral Amino Acid ◽  
Large Neutral Amino Acid ◽  
Post Exercise ◽  
Sled Dogs ◽  
Exercise Regimen ◽  
Acid Ratio

Tryptophan (Trp), an indispensable amino acid for dogs, is the precursor of serotonin, a neurotransmitter with a variety of effects throughout the body, including the ability to modulate cardiac and pulmonary activity. This study aimed to investigate the effects of a 12-week incremental exercise regimen and supplemental dietary Trp on heart rate (HR) and respiratory rate (RR) in client-owned sled dogs. Sixteen Siberian huskies were randomly allocated to either treatment or control diet groups. Both groups were fed a control diet (Trp to large neutral amino acid ratio of 0.047:1); however, treatment dogs received a Trp supplement to achieve a Trp to large neutral amino acid ratio of 0.075:1. Every three weeks, external telemetry equipment was used to non-invasively measure and record HR and RR at a resting, working, and post-exercise state in a controlled exercise challenge. A mixed model was used to test differences between diet, activity parameter, and week. Dietary Trp supplementation had no effect on HR or RR. Independent of diet, resting, working, post-exercise HR, and time to recover post-exercise HR decreased from week −1 to week 11 (p < 0.05). Resting HR had the greatest reduction from week −1 to week 11 (21%, p < 0.05). Working RR did not change with exercise (p > 0.10), but rRR and postRR decreased from week −1 to week 11 (p < 0.05). These data suggest that the exercise regimen the dogs were subjected to may have positively impacted the dogs’ capacity to sustain aerobic exercise, whereas Trp supplementation had no effect on HR or RR.

Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects

1990 ◽  
Vol 19 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Mark J. Russ ◽  
Sigurd H. Ackerman ◽  
Miriam Banay-Schwartz ◽  
Richard D. Shindledecker ◽  
Smith Gerard P.
Keyword(s):  
Amino Acid ◽  
Normal Subjects ◽  
Neutral Amino Acid ◽  
Large Neutral Amino Acid ◽  
Plasma Tryptophan

Plasma -tryptophan/neutral amino acid ratio and dexamethasone suppression in depression

1984 ◽  
Vol 11 (3) ◽  
pp. 185-192 ◽  
Author(s):  
Marshall S. Joseph ◽  
Timothy D. Brewerton ◽  
Victor I. Reus ◽  
Glenn T. Stebbins
Keyword(s):  
Amino Acid ◽  
Neutral Amino Acid ◽  
Plasma Tryptophan ◽  
Acid Ratio ◽  
Dexamethasone Suppression

Aspartame and Sucrose Produce a Similar Increase in the Plasma Phenylalanine to Large Neutral Amino Acid Ratio in Healthy Subjects

Pharmacology ◽  
1991 ◽  
Vol 43 (4) ◽  
pp. 210-219 ◽  
Author(s):  
Thomas S. Burns ◽  
Wayne Stargel ◽  
Christian Tschanz ◽  
Frank N. Kotsonis ◽  
Aryeh Hurwitz
Keyword(s):  
Amino Acid ◽  
Healthy Subjects ◽  
Neutral Amino Acid ◽  
Large Neutral Amino Acid ◽  
Similar Increase ◽  
Plasma Phenylalanine ◽  
Acid Ratio
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