The protective effects of L-ascorbic acid and DL-α-tocopherol on cultured rat embryos treated with xanthine/xanthine oxidase

Author(s):  
Anne J. Francis ◽  
Diana Anderson ◽  
P.C. Jenkinson ◽  
D.V.W. Parke
1999 ◽  
Vol 105 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Makoto Usami ◽  
Hirobumi Tabata ◽  
Yasuo Ohno
Keyword(s):  

2010 ◽  
Vol 28 (No. 5) ◽  
pp. 385-391 ◽  
Author(s):  
H. Wang ◽  
M.W. Martin ◽  
S. Yin

Isoflavone daidzein brings potential health benefits. Its antioxidant properties are considered to be responsible in part for its protective effects. We investigated the antioxidant effects of daidzein and its interactive effects with<br />&alpha;-tocopherol or ascorbic acid on Fe<sup>2+/</sup>ascorbate-induced oxidation of rat liver microsomes and copper-induced human low-density lipoprotein (LDL) oxidation. Although the inhibitory effect of daidzein on lipid peroxidation in microsome was weak, it effectively prevented LDL against oxidative modification by prolonging the lag time, decreasing the propagating rate, and suppressing malonaldehyde (MDA) and carbonyls formation. When daidzein was combined with &alpha;-tocopherol in microsomes oxidation and with ascorbic acid in LDL oxidation, the protection was significantly greater than the calculated additive effect of the two individual actions. Thus, daidzein can protect LDL from oxidative modification, and its combination with nutrients may be superior to the action of it alone. These results can help to get a better understanding of the interactions of different antioxidants in vivo.


2020 ◽  
Vol 58 (1) ◽  
pp. 107-115 ◽  
Author(s):  
Farzaneh Kianian ◽  
Seyed Morteza Karimian ◽  
Mehri Kadkhodaee ◽  
Nasrin Takzaree ◽  
Behjat Seifi ◽  
...  

2007 ◽  
Vol 1185 ◽  
pp. 68-74 ◽  
Author(s):  
Jung-Mi Han ◽  
Byung-Joon Chang ◽  
Tian-Zhu Li ◽  
Nong-Hoon Choe ◽  
Fu-Shi Quan ◽  
...  

2014 ◽  
Vol 35 (5) ◽  
pp. 466-477 ◽  
Author(s):  
Ming-Wei Chao ◽  
Pınar Erkekoglu ◽  
Chia-Yi Tseng ◽  
Wenjie Ye ◽  
Laura J. Trudel ◽  
...  

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