Synthesis of biindolyls by the reaction of indoles with indolin-2-ones and phosphoryl chloride or trifluoromethanesulfonic anhydride

Tetrahedron ◽  
1996 ◽  
Vol 52 (13) ◽  
pp. 4697-4708 ◽  
Author(s):  
David StC. Black ◽  
Andrew J. Ivory ◽  
Naresh Kumar
Keyword(s):  
Phosphoryl Chloride ◽  
Trifluoromethanesulfonic Anhydride

scholarly journals An efficient and practical chemo-enzymatic route to (3R,3aR,6R,6aR)-hexahydrofuro[3,2-b]furan-6-amino-3-ol (6-aminoisomannide) from renewable sources

SynOpen ◽  
2021 ◽  
Author(s):  
Valerio Zullo ◽  
Antonella Petri ◽  
Anna Iuliano
Keyword(s):  
Hydroxy Group ◽  
Sodium Azide ◽  
Hydroxyl Group ◽  
Azido Group ◽  
One Pot ◽  
Renewable Sources ◽  
Nucleophilic Displacement ◽  
Trifluoromethanesulfonic Anhydride ◽  
Enzymatic Route

The synthesis of 6-aminoisomannide is easily achieved starting from the renewable, inexpensive and commercially available isosorbide, in 66% overall yield. A biocatalysed highly regioselective acetylation of the 3-endo hydroxyl group of isosorbide was followed by the stereospecific interconversion of the 6-exo hydroxyl group into azido group, through reaction with trifluoromethanesulfonic anhydride followed by nucleophilic displacement of the triflate group by sodium azide. Finally, reduction of the azido group and deacetylation of the 3-hydroxy group were performed one pot by using LiAlH4.

A synthesis of alkylated 3-aminoisoquinolines and related compounds

1982 ◽  
Vol 35 (7) ◽  
pp. 1391 ◽  
Author(s):  
AJ Liepa
Keyword(s):  
Phosphoryl Chloride ◽  
Tertiary Amides ◽  
Derivatives Of ◽  
Related Compounds ◽  
Selection Of

N,N-Dialkyl derivatives of 3-aminoisoquinoline have been prepared by reaction of nitriles with various arylacetic acid tertiary amides in the presence of phosphoryl chloride. The synthesis has been extended to include a benzoisoquinoline and annulated isoquinolines by the selection of appropriate amide and nitrile precursors.

2-Iodosylbenzoic acid activated by trifluoromethanesulfonic anhydride: efficient oxidant and electrophilic reagent for preparation of iodonium salts

2021 ◽  
Author(s):  
Akira Yoshimura ◽  
Christopher Huss ◽  
Akio Saito ◽  
Tsugio Kitamura ◽  
Viktor V Zhdankin
Keyword(s):  
Electrophilic Reagent ◽  
Iodonium Salts ◽  
Trifluoromethanesulfonic Anhydride

2-Iodosylbenzoic acid in the presence of trifluoromethanesulfonic anhydride is an efficient oxidant and electrophilic reagent useful for preparation of the corresponding alkenyl and aryliodonium salts. Compared to the previously reported...

scholarly journals Raman and NMR Studies in the System Phosphoryl Chloride--Aluminium Chloride.

1993 ◽  
Vol 47 ◽  
pp. 344-357 ◽  
Author(s):  
Frank Birkeneder ◽  
Rolf Willestofte Berg ◽  
Niels Janniksen Bjerrum ◽  
Anna V. Luzikova ◽  
Jon Brunvoll ◽  
...  
Keyword(s):  
Aluminium Chloride ◽  
Phosphoryl Chloride ◽  
Nmr Studies
Sign in / Sign up

Export Citation Format

Share Document