scholarly journals Cold-adapted recombinants of influenza a virus in MDCK cells I. Development and characterization of A/Ann Arbor/6/60 × A/Alaska /6/77 recombinant viruses

Virology ◽  
1982 ◽  
Vol 119 (1) ◽  
pp. 82-95 ◽  
Author(s):  
Takato Odagiri ◽  
Dan C. DeBorde ◽  
Hunein F. Maassab
Keyword(s):  
Influenza A Virus ◽  
Influenza A ◽  
Mdck Cells ◽  
Cold Adapted ◽  
Recombinant Viruses ◽  
Ann Arbor

scholarly journals Cold-adapted reassortants of influenza A virus: Pathogenicity of A/Ann Arbor/6/60�A/Alaska/6/77 reassortant virusesIn vivo andIn vitro

1986 ◽  
Vol 91 (1-2) ◽  
pp. 53-60 ◽  
Author(s):  
A. W. Heath ◽  
H. F. Maassab ◽  
T. Odagiri ◽  
D. C. DeBorde ◽  
C. W. Potter
Keyword(s):  
Influenza A Virus ◽  
Influenza A ◽  
Cold Adapted ◽  
Ann Arbor

scholarly journals Palmitoylation of the Influenza A Virus M2 Protein Is Not Required for Virus Replication In Vitro but Contributes to Virus Virulence

2009 ◽  
Vol 83 (17) ◽  
pp. 8655-8661 ◽  
Author(s):  
Michael L. Grantham ◽  
Wai-Hong Wu ◽  
Erin N. Lalime ◽  
Maria E. Lorenzo ◽  
Sabra L. Klein ◽  
...  
Keyword(s):  
Influenza A Virus ◽  
Virus Replication ◽  
Influenza A ◽  
Mdck Cells ◽  
Cysteine Residue ◽  
M2 Protein ◽  
Recombinant Viruses ◽  
Virus Particles

ABSTRACT The influenza A virus M2 protein has important roles during virus entry and in the assembly of infectious virus particles. The cytoplasmic tail of the protein can be palmitoylated at a cysteine residue, but this residue is not conserved in a number of human influenza A virus isolates. Recombinant viruses encoding M2 proteins with a serine substituted for the cysteine at position 50 were generated in the A/WSN/33 (H1N1) and A/Udorn/72 (H3N2) genetic backgrounds. The recombinant viruses were not attenuated for replication in MDCK cells, Calu-3 cells, or in primary differentiated murine trachea epithelial cell cultures, indicating there was no significant contribution of M2 palmitoylation to virus replication in vitro. The A/WSN/33 M2C50S virus displayed a slightly reduced virulence after infection of mice, suggesting that there may be novel functions for M2 palmitoylation during in vivo infection.

scholarly journals Cold-Adapted Reassortants of Influenza A Virus in MDCK Cells

1983 ◽  
Vol 27 (2) ◽  
pp. 203-206 ◽  
Author(s):  
Takato Odagiri ◽  
Curt W. Smitka ◽  
Hunein F. Maassab
Keyword(s):  
Influenza A Virus ◽  
Influenza A ◽  
Mdck Cells ◽  
Cold Adapted

scholarly journals Comprehensive N ‐glycosylation analysis of the influenza A virus proteins HA and NA from adherent and suspension MDCK cells

FEBS Journal ◽  
2021 ◽  
Author(s):  
Alexander Pralow ◽  
Marcus Hoffmann ◽  
Terry Nguyen‐Khuong ◽  
Markus Pioch ◽  
René Hennig ◽  
...  
Keyword(s):  
Influenza A Virus ◽  
Influenza A ◽  
Mdck Cells ◽  
Virus Proteins

A human cell polarity protein Lgl2 regulates influenza A virus nucleoprotein exportation from nucleus in MDCK cells

2020 ◽  
Vol 45 (1) ◽  
Author(s):  
Jing Liu ◽  
Haiying Wang ◽  
Mengdan Fang ◽  
Xuexin Chen ◽  
Xiaobo Zeng
Keyword(s):  
Cell Polarity ◽  
Influenza A Virus ◽  
Human Cell ◽  
Influenza A ◽  
Mdck Cells
Sign in / Sign up

Export Citation Format

Share Document