Fetal placental blood flow after uterine artery ligation in the guinea-pig

Placenta ◽  
1989 ◽  
Vol 10 (5) ◽  
pp. 471
Author(s):  
A.M. Carter ◽  
A. Detmer
Neonatology ◽  
1986 ◽  
Vol 49 (3) ◽  
pp. 172-180 ◽  
Author(s):  
Thomas Jansson ◽  
Magnus Thordstein ◽  
Ingemar Kjellmer

1978 ◽  
Vol 53 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Lena Mårtensson ◽  
Per-Ove B. Sjöquist ◽  
Leif Bjellin ◽  
Anthony M. Carter

1982 ◽  
Vol 243 (3) ◽  
pp. H404-H409 ◽  
Author(s):  
S. A. Myers ◽  
J. W. Sparks ◽  
E. L. Makowski ◽  
G. Meschia ◽  
F. C. Battaglia

Blood flow measurements were made using radioactive microspheres in 14 unstressed, conscious, pregnant guinea pigs with gestational age ranging between 34 and 67 days. Within each litter placental blood flow (PBF) was positively correlated to fetal weight (FW), even after correcting for placental weight differences. Although the largest littermate was, on the average, only 30% larger than the smallest, its material placental blood flow was 95% greater. The PBF vs. FW relationship could be described by the allometric equation: PBF = Ai FW2.89 where Ai is a litter-specific coefficient. This study demonstrates that the placenta of the largest littermate is "hyperperfused" compared with its smaller siblings.


1984 ◽  
Vol 246 (2) ◽  
pp. H207-H212 ◽  
Author(s):  
A. R. Hohimer ◽  
J. M. Bissonnette ◽  
J. Metcalfe ◽  
T. A. McKean

Pygmy goats in the last third of pregnancy were trained to walk on a treadmill at rates up to 2.0 mph and up an inclination of 0-15 degrees. Electromagnetic flowmeters were placed unilaterally on a uterine artery, and measurements were made while the goats were standing quietly on the treadmill and during 5 min of exercise. Blood flow fell during exercise in all five animals studied, and this reduction was proportional to the level of exertion. At the highest level of exercise that these animals would voluntarily perform, uterine artery blood flow fell by 32 +/- 3 (SE) % (P less than 0.001) from control. In four additional animals the radioactive microsphere technique was used to measure uterine blood flow at rest and after 5-7 min of exercise. In these animals, exercise caused total uterine blood flow to fall by 18 +/- 10%; cotyledonary (placental) blood flow fell by 8 +/- 13%, while myoendometrial blood flow decreased by 52 +/- 12% (P less than 0.05). Thus nonplacental portions of the pregnant Pygmy goat uterus suffer major reductions in blood flow during exercise. This vasoconstriction may be due to exercise per se or to concomitant hypocapnia or hyperthermia. Singleton and twin kids born to animals that exercised were of normal birth weight.


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