Portal Vein Pulsatility as a Dynamic Marker of Venous Congestion Following Cardiac Surgery: An Interventional Study Using Positive End-Expiratory Pressure

We aimed to assess variations in the portal vein pulsatility index (PI) during mechanical ventilation following cardiac surgery. Method. After ethical approval, we conducted a prospective monocentric study at Amiens University Hospital. Patients under mechanical ventilation following cardiac surgery were enrolled. Doppler evaluation of the portal vein (PV) was performed by transthoracic echography. The maximum velocity (VMAX) and minimum velocity (VMIN) of the PV were measured in pulsed Doppler mode. The PI was calculated using the following formula (VMAX − VMIN)/(VMax). A positive end-expiratory pressure (PEEP) incremental trial was performed from 0 to 15 cmH2O, with increments of 5 cmH2O. The PI (%) was assessed at baseline and PEEP 5, 10, and 15 cmH2O. Echocardiographic and hemodynamic parameters were recorded. Results. In total, 144 patients were screened from February 2018 to March 2019 and 29 were enrolled. Central venous pressure significantly increased for each PEEP increment. Stroke volumes were significantly lower after PEEP incrementation, with 52 mL (50–55) at PEEP 0 cmH2O and 30 mL (25–45) at PEEP 15 cmH2O, (p < 0.0001). The PI significantly increased with PEEP incrementation, from 9% (5–15) at PEEP 0 cmH2O to 15% (5–22) at PEEP 5 cmH2O, 34% (23–44) at PEEP 10 cmH2O, and 45% (25–49) at PEEP 15 cmH2O (p < 0.001). Conclusion. In the present study, PI appears to be a dynamic marker of the interaction between mechanical ventilation and right heart pressure after cardiac surgery. The PI could be a useful noninvasive tool to monitor venous congestion associated with mechanical ventilation.

Unilateral axillary adenopathy induced by COVID-19 vaccine: US follow-up evaluation

Objectives This study was conducted in order to investigate COVID-19 vaccine influence on unilateral axillary lymph nodes, comparing nodal basal features with their characteristics after the first and second vaccination dose. Methods Ninety-one volunteer employees from our center who participated in the BNT162b2 (Pfizer-BioNTech) vaccination campaign were prospectively recruited. A total of three axillary ultrasound evaluations of the ipsilateral vaccinated arm were performed: before vaccination, the week after the first dose and the week after the second dose. The following findings were recorded: the total number of visible nodes, the maximum measurements of the diameter and cortex, Bedi’s classification, and color Doppler evaluation. The collected data were compared using paired-sample Student’s t-test for quantitative continuous variables and Wilcoxon rank-sum test for ordinal variables. Additional analyses were performed after classifying patients according to the previous history of COVID-19 disease. Differences among both groups were evaluated with the Mann–Whitney U test. Variables with a p value < 0.05 were considered statistically significant. Results Comparative analyses between the three US examinations showed a statistically significant augmentation of total visible nodes, maximum diameter, cortical thickness, grade of Bedi’s classification, and Doppler signal (p < 0.001). Analyses between patients with and without previous COVID-19 infection showed a higher lymph node response in naïve patients compared to those who were previously infected. Conclusions According to our results, both doses of COVID-19 vaccine induced an increase of all axillary lymph node parameters with statistically significant differences, especially in coronavirus-naïve patients. Key Points • Pfizer COVID-19 vaccine induces a high incidence of ipsilateral axillary lymphadenopathy. • US scan identified an increase of all lymph nodes parameters, especially in coronavirus-naïve patients.

Diagnostic Accuracy of Doppler Ultrasound Compared to Surgical Exploration in Torsion Testis

BACKGROUND Twisting of the spermatic cord resulting in ischemia of the testicles known as testicular torsion is a surgical emergency. Delay in diagnosis or surgery results in loss of testicles. Doppler ultrasound of scrotum is used in evaluating acute scrotum to support or rule out a diagnosis of torsion testis. Our study compares Doppler results with findings at exploration to finding out the accuracy of Doppler diagnosis in this scenario. METHODS This was a record based observational cross-sectional study. Out of all cases of acute scrotum presented to a tertiary care hospital over 14 months time, those patients with Doppler evaluation done were identified (n = 52) and their surgical findings were compared to the Doppler findings. Diagnostic accuracy of Doppler in diagnosing torsion testis was measured using sensitivity, specificity, accuracy, and predictive values. RESULTS Out of these 52 cases, 44 (84.6 %) were testicular torsion on exploration while remaining cases were epididymo-orchitis four (7.7 %) and testicular appendage torsion four (7.7 %). Among 44 cases of torsion testis, 31 (70.5 %) patients underwent orchiectomy (70.45 %) and in remaining 13 (29.5 %) orchiopexy was done. Sensitivity of Doppler to diagnose testicular torsion was 86.4 %, specificity was 87.5 % and accuracy was 86.54 %. Positive predictive value (PPV) was 97.4 % and negative predictive value (NPV) was 53.8 %. CONCLUSIONS Doppler ultrasound can be used as an adjunct to clinical findings in acute scrotum. High positive predictive value suggest that all Doppler diagnosed torsion should undergo emergency exploration as it will be correct in 97.5 % cases. If performing a Doppler study delays the definitive management, and if clinical findings are highly suggestive of testicular torsion, treating doctor can proceed to surgery without Doppler evaluation. KEY WORDS Doppler, Torsion Testis, Scrotum

Clinical accuracy of reverse Barbeau test in the diagnosis of radial artery occlusion after transradial catheterization

Background Radial artery occlusion is an infrequent complication of transradial catheterization. Assessment of radial artery occlusion is a critical aspect of clinical care, and it should be done with an additional test, commonly by a plethysmographic test (reverse Barbeau test) or ultrasound (Doppler), the last is the gold standard. The objective of this study was to evaluate the accuracy of the reverse Barbeau test in detecting radial artery occlusion after transradial catheterization. Methods A study carried out in two centers encompassing patients submitted to procedures by radial access. All patients received at least 5,000IU of heparin. Sheaths were immediately removed after the procedure, using a patent hemostasis protocol. Patency of the radial artery was verified by reverse Barbeau test and duplex Doppler evaluation within the first 24 hours. Results A total of 350 patients were enrolled, with a mean age of 61.7 (±9.7) years. Radial artery occlusion was verified after the procedure in 19 (5.4%) patients, using duplex Doppler scan. Application of reverse Barbeau test had the following results: 64.0% type A curve, 15.7% type B, 8.3% type C, and 12.0% type D (the last suggesting occlusion). With reverse Barbeau test, patients with confirmed occlusion by ultrasound evaluation, 21.1% would be missed by a false-negative test, and in the ones, without radial artery occlusion, 8.2% would be misdiagnosed as having it (sensibility 78.9%; specificity 91.8%). Conclusion Reverse Barbeau test has good accuracy to detect radial artery occlusion, and it is a good option for clinical day use, although using reverse Barbeau test results in the overestimation of radial artery occlusion.

COMPARATIVE STUDY OF USG B-MODE AND DOPPLER IN EVALUATION OF OVARIAN MASS LESIONS

Background: Ovarian cancer is highly lethal due to delayed detection. Ovarian lesions display a myriad of findings on imaging. Knowledge of these is essential to make a diagnosis or list the differentials. USG remains the mainstay imaging modality in this war on cancer. Aims & Objectives: To assess the diagnostic accuracy of USG B-mode and doppler in characterisation of ovarian mass lesions. Methods: 103 women with ovarian lesions were evaluated with USG B-mode and doppler. The interpretation was compared with histopathology reports wherever possible. Results: With sensitivity and NPV of 81.82% and 84.62% of USG B-mode, it is a good primary imaging modality. By showing an increase in specificity to 94.23%, PPV to 89.29% and accuracy to 87.06%, the addition of doppler in the evaluation acts as a tool in confirmation of malignancy. Conclusion: With good diagnostic performance, USG proves to be a good primary imaging modality. Also, doppler evaluation forms a promising add-on that can be considered.