Class I major histocompatibility complex antigen expression on early murine trophoblast and its induction by lymphokines in vitro

1987 ◽  
Vol 10 (4) ◽  
pp. 319-328 ◽  
Author(s):  
B.L. Drake ◽  
N.J.C. King ◽  
L.E. Maxwell ◽  
J.C. Rodger
Keyword(s):  
Major Histocompatibility Complex ◽  
Antigen Expression ◽  
Class I ◽  
Major Histocompatibility Complex Antigen ◽  
Major Histocompatibility ◽  
Histocompatibility Complex

Class I and class II major histocompatibility complex antigen expression on hepatocytes: A study in children with liver disease

Hepatology ◽  
1990 ◽  
Vol 12 (2) ◽  
pp. 224-232 ◽  
Author(s):  
Ava Lobo-Yeo ◽  
Giorgio Senaldi ◽  
Bernard Portmann ◽  
Alex P. Mowat ◽  
Giorgina Mieli-Vergani ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Liver Disease ◽  
Antigen Expression ◽  
Class Ii ◽  
Class I ◽  
Major Histocompatibility Complex Antigen ◽  
Major Histocompatibility ◽  
Histocompatibility Complex

scholarly journals Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice.

1981 ◽  
Vol 153 (2) ◽  
pp. 280-292 ◽  
Author(s):  
E J Jenkinson ◽  
W Van Ewijk ◽  
J J Owen
Keyword(s):  
Monoclonal Antibodies ◽  
Major Histocompatibility Complex ◽  
Nude Mice ◽  
Antigen Expression ◽  
Major Histocompatibility Complex Antigen ◽  
Major Histocompatibility ◽  
Histocompatibility Complex ◽  
Selection Of

The expression and distribution of antigens coded by the K and I regions of the major histocompatibility complex in the developing thymus of normal and nude mice has been investigated using monoclonal antibodies. Both immunohistological studies of intact rudiments and in vitro labeling of cultures derived from microdissected rudiments indicate that, while K region antigens are present on epithelial and mesenchymal elements, I region antigens are only detectable on the epithelium. This view is also substantiated by the selective absence of I region antigens in the abnormal nude thymic rudiment where the defect is considered to be epithelial in nature. The findings are considered in relation to the role of the thymus in providing an environment for the differentiation and selection of developing T cells, and it is proposed that the Ia-expressing epithelial elements play a central role in these functions.

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