The haemoglobin molecule: is it a useful model for a drug receptor?

1980 ◽  
Vol 1 (2) ◽  
pp. 307-312 ◽  
Author(s):  
P Goodford
Author(s):  
Lemont Kier

: This review focuses on the two-century old concept of proton hopping. Introduced in 1806 by Grottus, it has evolved into an explanation of great diversity in describing many functions in living systems. It is a process involving water, which expands on the belief that life exists only in the presence of water. This review describes the mechanism of the process as it carries information through water. A focus is initially made on the process in water in the nerve systems. The nature of the process in these systems is described as the passage of proton hopping in living systems. In drug-receptor encounters, proton hopping is initiated, carrying specific information from these specialized encounters. The review continues with an explanation of sleep, arising from an alteration in proton hopping. A similar phenomenon of the effect of general anesthetic agents is described, as they interfere with by proton hopping. Finally, memory functions are addressed in the realm of events carried by proton hopping.


2015 ◽  
Vol 36 (19) ◽  
pp. 2433-2441 ◽  
Author(s):  
Chunye Liu ◽  
Xuejiao Zhang ◽  
Hui Jing ◽  
Yanqing Miao ◽  
Lingzhi Zhao ◽  
...  

1964 ◽  
Vol 14 (4) ◽  
pp. 458-467 ◽  
Author(s):  
KEIJIRO TAKAGI ◽  
ISSEI TAKAYANAGI
Keyword(s):  

1991 ◽  
Vol 208 (2) ◽  
pp. 119-130 ◽  
Author(s):  
Christina Zech ◽  
Robert Staudinger ◽  
Johannes Mühlbacher ◽  
Hartmut Glossmann
Keyword(s):  

2001 ◽  
Vol 1525 (1-2) ◽  
pp. 180-190 ◽  
Author(s):  
Maris Lapinsh ◽  
Peteris Prusis ◽  
Alexandrs Gutcaits ◽  
Torbjörn Lundstedt ◽  
Jarl E.S. Wikberg

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