scholarly journals The role of the transition between neutral and basic forms of human serum albumin in the kinetics of the binding to warfarin

Author(s):  
Josephina M.H. Kremer ◽  
Gesina Bakker ◽  
Jaap Wilting
1989 ◽  
Vol 54 (2) ◽  
pp. 536-543 ◽  
Author(s):  
Josef Chmelík ◽  
Pavel Anzenbacher ◽  
Vítěz Kalous

The renaturation of the two main components of human serum albumin, i.e. of mercaptalbumin and nonmercaptalbumin, was studied polarographically. It has been demonstrated that renaturation of both proteins after 1-min denaturation in 8M urea is reversible. By contrast, renaturation after 200 min denaturation in 8M urea is an irreversible process; the characteristics of renatured mercaptalbumin differ more from the properties of the native protein than the characteristics of nonmercaptalbumin. The studies of the kinetics of renaturation of both proteins have shown that the renaturation can be represented by a two-state model. This means that the existence of stable intermediary products during the renaturation process was not determined polarographically.


Chirality ◽  
2002 ◽  
Vol 14 (5) ◽  
pp. 442-448 ◽  
Author(s):  
Ilona Fitos ◽  
J�lia Visy ◽  
Julianna Kardos

2018 ◽  
Vol 118 ◽  
pp. 1773-1780 ◽  
Author(s):  
Dzmitry Shcharbin ◽  
Elzbieta Pedziwiatr-Werbicka ◽  
Tatyana Serchenya ◽  
Sylwia Cyboran-Mikolajczyk ◽  
Lena Prakhira ◽  
...  

Author(s):  
Meng-Ying Li ◽  
Chang-Qing Xiao ◽  
Zi-Qiang Xu ◽  
Miao-Miao Yin ◽  
Qi-Qi Yang ◽  
...  

2020 ◽  
Vol 312 ◽  
pp. 113365 ◽  
Author(s):  
Mohd. Akram ◽  
Farah Ansari ◽  
Faizan Abul Qais ◽  
Kabir-ud-Din

Toxicon ◽  
2019 ◽  
Vol 168 ◽  
pp. 158-163 ◽  
Author(s):  
Anna Kutschenko ◽  
Hans Bigalke ◽  
Florian Wegner ◽  
Kai Wohlfarth

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