Studies on gas-phase negative ion/molecule reactions of relevance to ion mobility spectrometry: kinetic modelling of the reactions occuring in “clean” air

1992 ◽  
Vol 121 (1-2) ◽  
pp. 141-158 ◽  
Author(s):  
P. Watts
Keyword(s):  
Gas Phase ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Kinetic Modelling ◽  
Negative Ion ◽  
Ion Molecule Reactions ◽  
Clean Air

Gas-Phase Ion Mobility Studies of Amines and Polyether/Amine Complexes Using Tandem Quadrupole Ion Trap/Ion Mobility Spectrometry

2000 ◽  
Vol 6 (2) ◽  
pp. 213-218 ◽  
Author(s):  
Colin S. Creaser ◽  
John R. Griffiths ◽  
Brian M. Stockton
Keyword(s):  
Gas Phase ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Ion Trap ◽  
Quadrupole Ion Trap ◽  
Amine Complexes ◽  
Ion Molecule Reactions ◽  
Ion Mobility Spectra ◽  
Pharmacologically Active ◽  
Tandem Quadrupole

The gas-phase positive ion mobility spectra of isomeric amines and polyether/amine complexes have been measured using a tandem quadrupole ion trap/ion mobility spectrometer. Ion mobilities of isomeric amines in helium, determined relative to benzene at pressures in the range 1–2 Torr, vary with the structure of the amine. The ability of quadrupole ion trap/ion mobility spectrometry to differentiate between a pharmacologically-active substance and an associated isomeric amine is demonstrated. Non-covalent complexes of cyclic and acyclic polyethers with protonated amines were generated by ion/molecule reactions in the ion trap and analysed by ion mobility spectrometry. The ion mobilities in helium may be interpreted in terms of the preferred conformations for these complexes. The use of polyether hosts as shift compounds for enhancing the relative mobilities of small amine guest ions is proposed.

scholarly journals Gas Phase Stability of Protein Ions in a Cyclic Ion Mobility Spectrometry Traveling Wave Device

2019 ◽  
Vol 91 (12) ◽  
pp. 7554-7561 ◽  
Author(s):  
Charles Eldrid ◽  
Jakub Ujma ◽  
Symeon Kalfas ◽  
Nick Tomczyk ◽  
Kevin Giles ◽  
...  
Keyword(s):  
Gas Phase ◽  
Ion Mobility Spectrometry ◽  
Phase Stability ◽  
Ion Mobility ◽  
Traveling Wave ◽  
Protein Ions ◽  
Wave Device
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