Pesticide Chemistry: Human Welfare and The Environment: Vol. 1. Synthesis and Structure-Activity Relationships; Vol. 2. Natural Products; Vol. 3. Mode of Action, Metabolism and Toxicology; Vol. 4. Pesticide Residues and Formulation Chemistry

1984 ◽  
Vol 22 (12) ◽  
pp. 1015-1016
Keyword(s):  
Natural Products ◽  
Pesticide Residues ◽  
Mode Of Action ◽  
Human Welfare ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Characterizing the structure–activity relationships of natural products, tanshinones, reveals their mode of action in inhibiting spleen tyrosine kinase

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2453-2461
Author(s):  
Min-Che Tung ◽  
Keng-Chang Tsai ◽  
Kit-Man Fung ◽  
Ming-Jaw Don ◽  
Tien-Sheng Tseng
Keyword(s):  
Natural Products ◽  
Protein Kinase ◽  
Tyrosine Kinase ◽  
Mode Of Action ◽  
Drug Target ◽  
Receptor Protein ◽  
Inflammatory Disorder ◽  
Spleen Tyrosine Kinase ◽  
Structure Activity Relationships ◽  
Structure Activity

The cytosolic non-receptor protein kinase, spleen tyrosine kinase (SYK), is an attractive drug target in autoimmune, inflammatory disorder, and cancers indications.

Perspective on FTY720, an Immunosuppressant

Synthesis ◽  
2018 ◽  
Vol 50 (05) ◽  
pp. 968-983 ◽  
Author(s):  
Sivaraman Balasubramaniam ◽  
Ganapathy Sankaran ◽  
Sneh Badle
Keyword(s):  
Chemical Modification ◽  
Mode Of Action ◽  
Immunosuppressive Drugs ◽  
Binding Studies ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Fingolimod Hydrochloride

FTY720 {fingolimod hydrochloride, 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride}, a novel immunosuppressant, was discovered by chemical modification based on the structure activity relationships of ISP-I (myriocin), a metabolite of the fungus Isaria­ sinclairii. This short perspective provides insights to the various strategies available in the literature for the synthesis of FTY720 and its analogues.1 Introduction2 Classification of Immunosuppressive Drugs3 The Rise of FTY7204 Different Synthetic Strategies for FTY7205 Analogues of FTY7206 Binding Studies of FTY7207 Mode of Action8 Conclusion

Spasmolytic Effects, Mode of Action, and Structure−Activity Relationships of Stilbenoids fromNidema boothii†,⊥

2004 ◽  
Vol 67 (2) ◽  
pp. 160-167 ◽  
Author(s):  
Yanet Hernández-Romero ◽  
Juana-Isela Rojas ◽  
Rafael Castillo ◽  
Alejandra Rojas ◽  
Rachel Mata
Keyword(s):  
Mode Of Action ◽  
Structure Activity Relationships ◽  
Structure Activity
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