Inhibition by intrathecal prazosin but not yohimbine of fentanyl-induced muscular rigidity in the rat

1995 ◽  
Vol 201 (2) ◽  
pp. 167-170 ◽  
Author(s):  
Ping-Wing Lui ◽  
Le-Yin Tsen ◽  
Miin-Jiuan Fu ◽  
Chiu-Ping Yeh ◽  
Tak-Yu Lee ◽  
...  
Keyword(s):  
Muscular Rigidity

Stiff Person Syndrome

2013 ◽  
Author(s):  
Aaron E. Miller ◽  
Teresa M. DeAngelis
Keyword(s):  
Diagnostic Criteria ◽  
Clinical Features ◽  
Therapeutic Options ◽  
Stiff Person Syndrome ◽  
Muscular Rigidity ◽  
Unexplained Pain ◽  
Electrophysiological Tests

Stiff person syndrome is an important autoimmune mediated disorder to consider in patients with unexplained pain and muscular rigidity. We review the proposed diagnostic criteria, common clinical features, and important serologic and electrophysiological tests to aid in diagnosis as well as medical and rehabilitative therapeutic options. In addition, we discuss the identification and management of possible paraneoplastic presentations.

Neuroleptic Malignant Syndrome in Striatonigral Degeneration

1988 ◽  
Vol 153 (2) ◽  
pp. 254-255 ◽  
Author(s):  
W. R. G. Gibb
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Heat Production ◽  
Striatal Dopamine ◽  
Striatonigral Degeneration ◽  
Muscular Rigidity

A case of probable neuroleptic malignant syndrome (NMS) complicating l-dopa withdrawal in striatonigral degeneration is described. This case suggests that the hyperthermia of NMS is due to peripheral heat production associated with severe muscular rigidity secondary to withdrawal of striatal dopamine drive, rather than being centrally mediated by the hypothalamus, which is not involved in striatonigral degeneration.

The Aftercare of the Patient with the Neuroleptic Malignant Syndrome

1985 ◽  
Vol 146 (3) ◽  
pp. 317-318 ◽  
Author(s):  
Dov Aizenberg ◽  
Arieh Shalev ◽  
Hanan Munitz
Keyword(s):  
Neuroleptic Malignant Syndrome ◽  
Autonomic Dysfunction ◽  
Neuroleptic Drugs ◽  
Anti Psychotic ◽  
Idiosyncratic Reaction ◽  
Muscular Rigidity ◽  
Level Of Consciousness

SummaryThe neuroleptic malignant syndrome (NMS) is an idiosyncratic reaction to neuroleptic drugs, made up of hyperthermia, muscular rigidity, disturbance of level of consciousness and autonomic dysfunction. It is potentially lethal and should be kept in mind whilst using anti-psychotic drugs; as most patients treated by them require further anti-psychotic treatment, the clinician faces the problem of treating those patients after a NMS episode, yet reports in the literature have generally neglected the problem of late management. A patient suffering from a psychosis and NMS is presented, and a rationale for management offered.

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