Solid-phase extraction method for the determination of diltiazem and its metabolites by high-performance liquid chromatography: fact or fallacy?

Author(s):  
R. Boulieu
RSC Advances ◽  
2021 ◽  
Vol 11 (27) ◽  
pp. 16297-16306
Author(s):  
Maizatul Najwa Jajuli ◽  
Grégoire Herzog ◽  
Marc Hébrant ◽  
Ng Eng Poh ◽  
Afidah Abdul Rahim ◽  
...  

A bar micro-solid phase (bar μ-SPE) extraction method using either graphene or zeolite or their mixtures as an adsorbent, coupled with high-performance liquid chromatography was developed for the determination of pharmaceutical compounds of diverse polarity.


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