Synergistic interactions of gentamicin and pure tones causing cochlear hair cell loss in pigmented guinea pigs

1988 ◽  
Vol 36 (2-3) ◽  
pp. 249-259 ◽  
Author(s):  
Peter W.P Collins
Keyword(s):  
Hair Cell ◽  
Guinea Pigs ◽  
Cell Loss ◽  
Hair Cell Loss ◽  
Cochlear Hair Cell ◽  
Synergistic Interactions ◽  
Pure Tones

Permanent Threshold Shift and Cochlear Hair Cell Loss in the Kanamycin-Treated Guinea Pig

1978 ◽  
Vol 86 (6) ◽  
pp. ORL-886-ORL-887 ◽  
Author(s):  
Cynthia A. Prosen ◽  
Michael R. Petersen ◽  
David. B. Moody ◽  
William C. Stebbins ◽  
Joseph E. Hawkins
Keyword(s):  
Guinea Pig ◽  
Hair Cell ◽  
Hair Cells ◽  
Guinea Pigs ◽  
Cell Loss ◽  
Outer Hair Cells ◽  
Hair Cell Loss ◽  
Hearing Sensitivity ◽  
Cochlear Hair Cell ◽  
Differential Contribution

The differential contribution of the inner hair cells (IHC) and the outer hair cells (OHC) in the mammalian cochlea to hearing sensitivity was assessed in six behaviorally-trained guinea pigs by comparing audiograms preadministration and postadministration of kanamycin, an antibiotic that predominantly destroys guinea pig OHC while leaving the IHC structurally unchanged. The results support the hypothesis that only the IHC of the cochlea responds to tones approximately 50 to 60 dB above the threshold of the intact cochlea.

Age-Related Cochlear Hair Cell Loss in the Chinchilla

1985 ◽  
Vol 94 (1) ◽  
pp. 75-80 ◽  
Author(s):  
Tapan K. Bhattacharyya ◽  
Vijay S. Dayal
Keyword(s):  
Hair Cell ◽  
Cell Loss ◽  
Hair Cell Loss ◽  
Cochlear Hair Cell ◽  
Age Related

scholarly journals Behavioral Disturbances and Hair Cell Loss in the Inner Ear Following Nitrile Exposure in Mice, Guinea Pigs, and Frogs

2006 ◽  
Vol 96 (1) ◽  
pp. 123-132 ◽  
Author(s):  
C. Soler-Martin ◽  
N. Diez-Padrisa ◽  
P. Boadas-Vaello ◽  
J. Llorens
Keyword(s):  
Hair Cell ◽  
Inner Ear ◽  
Guinea Pigs ◽  
Cell Loss ◽  
Hair Cell Loss ◽  
Behavioral Disturbances

Threshold Shift, Hair Cell Loss, and Hair Bundle Stiffness Following Exposure to 120 and 125 dB Pure Tones in the Neonatal Chick

1992 ◽  
Vol 112 (3) ◽  
pp. 444-454 ◽  
Author(s):  
Henry J. Adler ◽  
J. F. X. Kenealy ◽  
Robert M. Dedio ◽  
James C. Saunders
Keyword(s):  
Hair Cell ◽  
Cell Loss ◽  
Threshold Shift ◽  
Hair Bundle ◽  
Hair Cell Loss ◽  
Neonatal Chick ◽  
Pure Tones

scholarly journals Designer aminoglycosides prevent cochlear hair cell loss and hearing loss

2015 ◽  
Vol 125 (2) ◽  
pp. 583-592 ◽  
Author(s):  
Markus E. Huth ◽  
Kyu-Hee Han ◽  
Kayvon Sotoudeh ◽  
Yi-Ju Hsieh ◽  
Thomas Effertz ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hair Cell ◽  
Cell Loss ◽  
Hair Cell Loss ◽  
Cochlear Hair Cell

Comparative Study of Age-Related Cochlear Hair Cell Loss

1986 ◽  
Vol 95 (5) ◽  
pp. 510-513 ◽  
Author(s):  
Vijay S. Dayal ◽  
Tapan K. Bhattacharyya
Keyword(s):  
Hair Cell ◽  
Organ Of Corti ◽  
Surface Preparation ◽  
Cell Loss ◽  
Squirrel Monkeys ◽  
Hair Cell Loss ◽  
Human Organ ◽  
Cochlear Hair Cell ◽  
Histological Damage ◽  
Age Related

Age-related hair cell loss has been studied in squirrel monkeys using surface preparation of the organ of Corti. Increasing hair cell loss starting at the apex is seen as a function of age. This finding is discussed in the light of our studies in guinea pigs, chinchillas, and rabbits. Reviewed with other human and experimental data, it would appear that many species of animals have age-related histological damage similar to that seen in the human organ of Corti.

Chinchilla models of selective cochlear hair cell loss

2002 ◽  
Vol 174 (1-2) ◽  
pp. 230-238 ◽  
Author(s):  
Sandra L McFadden ◽  
Dalian Ding ◽  
Haiyan Jiang ◽  
Jenifer M Woo ◽  
Richard J Salvi
Keyword(s):  
Hair Cell ◽  
Cell Loss ◽  
Hair Cell Loss ◽  
Cochlear Hair Cell
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