Estimated contribution of coronary artery bypass graft surgery to the decline in coronary heart disease mortality: The Minnesota heart survey

The objective of our study was to investigate the features of circulatory autonomic regulation in the patients with a coronary artery bypass graft surgery (CABG) or correction of a valvular heart disease (CVHD). Material and Methods. Our study enrolled 42 patients (including 12 women) aged 63 (57; 67), who underwent CABG; and 36 patients (including 16 women) aged 58 (47; 65), who underwent CVHD. Simultaneous 15-minute recordings of electrocardiograms and photoplethysmograms (PPG) were performed on all patients before and after the surgery. We assessed and analyzed statistical and frequency-related measures of heart rate variability (HRV) and index of synchronization (S) among low-frequency (LF) oscillations in HRV and PPG. Results. The values of most autonomic regulation indices in our study did not have statistically significant differences among the patients with CABG and CVHD at all stages of research. The exception was represented by the heart rate, which was higher before CVHD (p=0.013). Conclusion. In all patients with CABG, the values of HRV and S did not depend on the differences in their clinical statuses or performed cardiac surgical interventions.

Download Full-text

Prevalence of carotid artery stenosis in ischaemic heart disease patients in Bangladesh

SAGE Open Medicine ◽

10.1177/2050312119830838 ◽

2019 ◽

Vol 7 ◽

pp. 205031211983083

Author(s):

Dipannita Adhikary ◽

Redoy Ranjan ◽

Sabita Mandal ◽

Mohammad Delwer Hossain Hawlader ◽

Dipak Kumar Mitra ◽

...

Keyword(s):

Heart Disease ◽

Coronary Artery ◽

Carotid Artery ◽

Coronary Artery Bypass Graft ◽

Coronary Artery Bypass ◽

Carotid Artery Stenosis ◽

Artery Bypass ◽

Bypass Graft ◽

Artery Stenosis ◽

Artery Bypass Graft

Background: Concurrent carotid artery stenosis and ischaemic heart disease rates are increasing day by day in Bangladesh. Moreover, carotid artery stenosis has been identified as a high-risk factor for postoperative ischaemic cerebral inconvenience following coronary artery bypass graft surgery. Methods: This observational cross-sectional study was performed to evaluate 200 study patients from July 2017 to June 2018. Patients with coronary artery disease scheduled for isolated elective coronary artery bypass graft surgery were included in the study, excluding those with coexisting valvular or congenital heart disease and emergency coronary artery bypass graft surgery. Results: About two-thirds of the study patients were 50–59 years old, with a mean age of 57.7 ± 3.06 years. Approximately 70% patients were male; the male:female ratio was 2.1:1. Most of the patients (74.5%) were Muslim. The majority of patients (59.0%) were overweight, and severe carotid artery stenosis was significantly higher in obese patients (p ⩽ 0.05). Furthermore, hypertension and diabetes mellitus were significantly associated with moderate to severe carotid artery stenosis (p ⩽ 0.05). Multi-vessel coronary artery disease was significantly associated with the severity of carotid artery stenosis. Bilateral carotid artery stenosis was significantly associated with the severity of carotid artery stenosis (p ⩽ 0.05). Conclusion: Routine duplex screening will identify significant carotid artery disease and will subsequently reduce the risk of perioperative stroke in ischaemic heart disease patients undergoing coronary artery bypass graft surgery.

Download Full-text

Effects of off-pump coronary artery bypass graft on the clinical efficacy, surgical indicators, and cardiac function of patients with coronary heart disease

Annals of Palliative Medicine ◽

10.21037/apm-20-2560 ◽

2021 ◽

Vol 10 (1) ◽

pp. 597-605

Author(s):

Jie Ma ◽

Hong-Juan Liao ◽

Feng-Wu Shi ◽

Jing-Hui An ◽

Shu-Guang Zhao ◽

...

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Coronary Artery ◽

Cardiac Function ◽

Coronary Artery Bypass Graft ◽

Artery Bypass ◽

Bypass Graft ◽

Artery Bypass Graft ◽

Off Pump ◽

Pump Coronary Artery Bypass

Download Full-text

Effectiveness of the fixed-dose combination therapy with perindopril and amlodipine in coronary heart disease patients after coronary artery bypass graft surgery

CARDIOVASCULAR THERAPY AND PREVENTION ◽

10.15829/1728-8800-2011-6-47-54 ◽

2011 ◽

Vol 10 (6) ◽

pp. 47-54

Author(s):

B. G. Iskenderov ◽

O. N. Sisina ◽

O. A. Kameneva

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Coronary Artery ◽

Combination Therapy ◽

Coronary Artery Bypass Graft ◽

Artery Bypass ◽

Bypass Graft ◽

Fixed Dose ◽

Artery Bypass Graft ◽

Dose Combination

Aim. To study the effectiveness of the fixed-dose combination therapy with perindopril and amlodipine (Prestance 5/5 mg/d) in coronary heart disease (CHD) patients after coronary artery bypass graft (CABG) surgery. Material and methods. The clinical trial included 65 patients (37 men, 28 women aged 45-68 years; mean age 56,3±3,5 years) after CABG. All patients were randomised into two groups: the control group (CG; n=35) and the main group (MG; n=30). Both groups received antiplatelet agents and statins, while the MG patients additionally received Prestance (5/5 mg/d). Prestance therapy started three-four weeks after CABG and lasted for four months. All participants underwent 24-hour monitoring of ECG and blood pressure (BP), Doppler echocardiography, and Doppler ultrasound of brachial and common carotid arteries. Results. Compared to the CG, the MG demonstrated decreased incidence of pain and painless ischemia episodes, reduced maximal ST segment depression and its total duration, and increased rate threshold of myocardial ischemia. In addition, Prestance therapy was associated with improved systolic and diastolic heart function and significantly improved endothelium-dependent vasodilatation. In patients with normal BP, Prestance (5/5 mg/d) did not cause hypotension, but reduced excessive BP variability. In the MG, acute coronary syndrome (ACS) was registered in 1 individual (3,3 %), while in the CG, it was registered in 4 patients (11.4 %), and in 3 cases, coronary artery stenting was performed. Conclusion. In patients with normal BP, Prestance (5/5 mg/d) therapy in the early post-CABG period had a pronounced anti-ischemic, cardio- and vasoprotective effects, and also prevented excessive BP variability.

Download Full-text