Reduced blood lass following open heart surgery with aprotinin (trasylol) is associated with an increase in intraoperative activated clotting time (ACT)

1989 ◽  
Vol 3 (5) ◽  
pp. 80 ◽  
Author(s):  
D. Royston ◽  
B.P. Bidstrup ◽  
K.M. Taylor ◽  
R.M. Sapsford
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Clotting Time ◽  
Activated Clotting Time

SEASONAL VARIATION IN THE EFFECT OF A FIXED DOSE OF HEPARIN ON ACTIVATED CLOTTING TIME IN PATIENTS PREPARED FOR OPEN-HEART SURGERY*

2001 ◽  
Vol 18 (5) ◽  
pp. 865-873 ◽  
Author(s):  
Ugur Hodoglugil ◽  
Berrin Gunaydin ◽  
Sahin Yardim ◽  
Hakan Zengil ◽  
Michael H. Smolensky
Keyword(s):  
Seasonal Variation ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Fixed Dose ◽  
Open Heart ◽  
Clotting Time ◽  
Activated Clotting Time

Anticoagulation management in patients undergoing open heart surgery by activated clotting time and whole blood heparin concentration

Perfusion ◽  
2006 ◽  
Vol 21 (5) ◽  
pp. 285-290 ◽  
Author(s):  
Pappalardo Federico ◽  
Franco Annalisa ◽  
Crescenzi Giuseppe ◽  
De Simone Francesco ◽  
Torracca Lucia ◽  
...  
Keyword(s):  
Whole Blood ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Clotting Time ◽  
Anticoagulation Management ◽  
Heparin Concentration ◽  
Activated Clotting Time

scholarly journals Evaluation of the activated clotting time to control heparin and protamine dosage in open-heart surgery

1978 ◽  
Vol 75 (5) ◽  
pp. 790-791 ◽  
Author(s):  
Charles F. Arkin ◽  
Mehran Shahsavari ◽  
Bradley E. Copeland ◽  
Agnes Kim
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Clotting Time ◽  
Activated Clotting Time

Heparin Concentrations Correlated To The Activated Whole Blood Clotting Time (Act) During Extracorporeal Circulation

1981 ◽  
Author(s):  
S Stenbjerg ◽  
E Berg ◽  
O K Albrechtsen
Keyword(s):  
Extracorporeal Circulation ◽  
Whole Blood ◽  
Blood Clotting ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart ◽  
Excellent Correlation ◽  
Clotting Time ◽  
Automated Method ◽  
Blood Clotting Time

Heparin levels and ACT were followed during open heart surgery in lo patients. Heparin was assayed by an amidolytic method using substrate S-2222. ACT was determined with an automated method using celite and glass beads as activators of coagulation. Neither the hemodilution nor the depletion of platelets observed during extracorporeal circulation seemed to influence the ACT. An excellent correlation between the ACT and the actual heparin level was found in each patient with coefficients of correlation ranging from 0.73 – 0.97. A slightly better correlation was noticed for values of ACT below 600 seconds. It was concluded that the ACT is a valuable and reliable tool in control of heparinisation during open heart surgery.

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