Anticoagulation management in patients undergoing open heart surgery by activated clotting time and whole blood heparin concentration

Perfusion ◽  
2006 ◽  
Vol 21 (5) ◽  
pp. 285-290 ◽  
Author(s):  
Pappalardo Federico ◽  
Franco Annalisa ◽  
Crescenzi Giuseppe ◽  
De Simone Francesco ◽  
Torracca Lucia ◽  
...  
1981 ◽  
Author(s):  
S Stenbjerg ◽  
E Berg ◽  
O K Albrechtsen

Heparin levels and ACT were followed during open heart surgery in lo patients. Heparin was assayed by an amidolytic method using substrate S-2222. ACT was determined with an automated method using celite and glass beads as activators of coagulation. Neither the hemodilution nor the depletion of platelets observed during extracorporeal circulation seemed to influence the ACT. An excellent correlation between the ACT and the actual heparin level was found in each patient with coefficients of correlation ranging from 0.73 – 0.97. A slightly better correlation was noticed for values of ACT below 600 seconds. It was concluded that the ACT is a valuable and reliable tool in control of heparinisation during open heart surgery.


2001 ◽  
Vol 18 (5) ◽  
pp. 865-873 ◽  
Author(s):  
Ugur Hodoglugil ◽  
Berrin Gunaydin ◽  
Sahin Yardim ◽  
Hakan Zengil ◽  
Michael H. Smolensky

1978 ◽  
Vol 75 (5) ◽  
pp. 790-791 ◽  
Author(s):  
Charles F. Arkin ◽  
Mehran Shahsavari ◽  
Bradley E. Copeland ◽  
Agnes Kim

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