Inverse Agonist Activity of Steroidogenic Factor SF-1

2010 ◽  
pp. 245-259 ◽  
Author(s):  
Fabrice Piu ◽  
Andria L. Del Tredici
Keyword(s):  
Inverse Agonist ◽  
Agonist Activity

Corrigendum to “Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor” [Eur. J. Pharmacol. 495 (2004) 87–96]

2004 ◽  
Vol 502 (1-2) ◽  
pp. 157
Author(s):  
Daniele V.S. Lopes ◽  
Rodrigo R.B. Caruso ◽  
Newton G. Castro ◽  
Paulo R.R. Costa ◽  
Alcides J.M. da Silva ◽  
...  
Keyword(s):  
Benzodiazepine Receptor ◽  
Inverse Agonist ◽  
Agonist Activity ◽  
Central Benzodiazepine Receptor

Identification of a CCK-B/GASTRIN receptor amino acid determinant of inverse agonist activity

2000 ◽  
Vol 118 (4) ◽  
pp. A308
Author(s):  
John S. Pratt ◽  
Mathieu Goumain ◽  
Kirsten Schaffer ◽  
Ci Chen ◽  
Martin Beinborn ◽  
...  
Keyword(s):  
Amino Acid ◽  
Inverse Agonist ◽  
Agonist Activity ◽  
Gastrin Receptor

Inverse agonist activity of agouti and agouti-related protein

Peptides ◽  
2003 ◽  
Vol 24 (4) ◽  
pp. 603-609 ◽  
Author(s):  
Biao-Xin Chai ◽  
Richard R. Neubig ◽  
Glenn L. Millhauser ◽  
Darren A. Thompson ◽  
Pilgrim J. Jackson ◽  
...  
Keyword(s):  
Inverse Agonist ◽  
Agonist Activity ◽  
Related Protein ◽  
Agouti Related Protein

Antipsychotics with inverse agonist activity at the dopamine D3 receptor

1996 ◽  
Vol 103 (10) ◽  
pp. 1163-1175 ◽  
Author(s):  
N. Griffon ◽  
C. Pilon ◽  
F. Sautel ◽  
J. -C. Schwartz ◽  
P. Sokoloff
Keyword(s):  
Inverse Agonist ◽  
Dopamine D3 Receptor ◽  
D3 Receptor ◽  
Agonist Activity ◽  
Dopamine D3

scholarly journals Effects of N-Substituents on the Functional Activities of Naltrindole Derivatives for the δ Opioid Receptor: Synthesis and Evaluation of Sulfonamide Derivatives

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 3792
Author(s):  
Chiharu Iwamatsu ◽  
Daichi Hayakawa ◽  
Tomomi Kono ◽  
Ayaka Honjo ◽  
Saki Ishizaki ◽  
...  
Keyword(s):  
Molecular Mechanism ◽  
Opioid Receptor ◽  
Inverse Agonist ◽  
Side Chain ◽  
Agonist Activity ◽  
Inverse Agonists ◽  
Functional Activities ◽  
Δ Opioid Receptor

We have recently reported that N-alkyl and N-acyl naltrindole (NTI) derivatives showed activities for the δ opioid receptor (DOR) ranging widely from full inverse agonists to full agonists. We newly designed sulfonamide-type NTI derivatives in order to investigate the effects of the N-substituent on the functional activities because the side chain and S=O part in the sulfonamide moiety located in spatially different positions compared with those in the alkylamine and amide moieties. Among the tested compounds, cyclopropylsulfonamide 9f (SYK-839) was the most potent full inverse agonist for the DOR, whereas phenethylsulfonamide 9e (SYK-901) showed full DOR agonist activity with moderate potency. These NTI derivatives are expected to be useful compounds for investigation of the molecular mechanism inducing these functional activities.

Inverse Agonist Activity of Sarpogrelate, a Selective 5-HT2A-Receptor Antagonist, at the Constitutively Active Human 5-HT2A Receptor

2006 ◽  
Vol 102 (2) ◽  
pp. 189-195 ◽  
Author(s):  
Habib Abul Muntasir ◽  
Mohiuddin Ahmed Bhuiyan ◽  
Masaji Ishiguro ◽  
Masanobu Ozaki ◽  
Takafumi Nagatomo
Keyword(s):  
Receptor Antagonist ◽  
Inverse Agonist ◽  
Agonist Activity ◽  
Constitutively Active

scholarly journals BAY36-7620: A Potent Non-Competitive mGlu1 Receptor Antagonist with Inverse Agonist Activity.

2001 ◽  
Vol 59 (5) ◽  
pp. 965-973 ◽  
Author(s):  
Fiona Y. Carroll ◽  
Andreas Stolle ◽  
Philip M. Beart ◽  
Arnd Voerste ◽  
Isabelle Brabet ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Inverse Agonist ◽  
Agonist Activity ◽  
Mglu1 Receptor
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