Azetidine-2-carboxylic acid and other nonprotein amino acids in the pathogenesis of neurodevelopmental disorders

Author(s):  
Edward Rubenstein
2007 ◽  
Vol 62 (11) ◽  
pp. 1453-1458 ◽  
Author(s):  
Yusuf M. Al-Hiari ◽  
Ali M. Qaisia ◽  
Mohammad Y.Abu Shuheil ◽  
Mustafa M. El-Abadelah ◽  
Wolfgang Voelter

The reaction of 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (7) with each of sarcosine and (±)-pipecolinic acid afforded the corresponding N-(4- oxoquinolin-7-yl)-α-amino acids 8 and 9. Reductive lactamization of the latter with sodium dithionite gave hexahydropyrido[2,3- f ]quinoxaline (10) and octahydrodipyrido[1,2-a : 2,3- f ]quinoxaline (11) derivatives, respectively. Compounds 8 - 11 and their homologs 1 - 6, accessible from (S)-proline, (2S, 4R)-4-hydroxyproline and (S)-tetrahydroisoquinoline-3-carboxylic acid exhibit good to excellent antibacterial activities against E. coli and S. aureus.


2009 ◽  
Vol 20 (16) ◽  
pp. 1940-1947 ◽  
Author(s):  
Giuseppe Cremonesi ◽  
Piero Dalla Croce ◽  
Alessandra Forni ◽  
Maddalena Gallanti ◽  
Raffaella Gandolfi ◽  
...  

1977 ◽  
Vol 30 (5) ◽  
pp. 383-387 ◽  
Author(s):  
ICHIRO MURAMATSU ◽  
YOSHIAKI MOTOKI ◽  
MASAAKI AOYAMA ◽  
HIDEO SUZUKI

2017 ◽  
Vol 23 (9) ◽  
pp. 716-726 ◽  
Author(s):  
Anna Kusakiewicz-Dawid ◽  
Monika Porada ◽  
Wioletta Ochędzan-Siodłak ◽  
Małgorzata A. Broda ◽  
Maciej Bujak ◽  
...  

1982 ◽  
Vol 37 (7-8) ◽  
pp. 584-586 ◽  
Author(s):  
Rudy Susilo ◽  
Rolf Gmelin

Abstract Two sulphur containing amino acids, dichrostachinic acid and djenkolic acid, and one sulphur containing imino acid, thiazolidine-4-carboxylic acid, have been isolated from the seeds o f Parkia speciosa Hassk. Dichrostachinic acid and djenkolic cyclic polysulphides in Parkia speciosa Hassk.


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