Case reports involving the use of lysergic acid diethylamide

2020 ◽  
pp. 313-315
Author(s):  
Diane M. Boland
Keyword(s):  
Case Reports ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide

Improvement of hallucinogen persisting perception disorder (HPPD) with oral risperidone: case report

2013 ◽  
Vol 31 (1) ◽  
pp. 47-49 ◽  
Author(s):  
N. Subramanian ◽  
M. Doran
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide ◽  
Oral Risperidone ◽  
Perception Disorder

We describe a 38-year-old woman who developed symptoms of hallucinogen persisting perception disorder (HPPD) after using lysergic acid diethylamide (LSD) once and continued to have symptoms of HPPD for nearly 17 years, although she did not use LSD after her first use. The symptoms of HPPD were temporally related to her first LSD use and she responded well to risperidone within a few weeks of commencing on the same. Although different medications have been tried in the management of HPPD including risperidone, olanzapine, clonidine, fluoxetine, sertraline, benzodiazepines and anti-epileptic medications, none have been proven to be the definitive medication of choice in the treatment of HPPD. Furthermore, there have been case reports suggesting worsening of symptoms with risperidone; however, the response to risperidone in our patient suggests the possibility of its effectiveness in the management of HPPD symptoms in some patients.

scholarly journals Changes in Online Psychoactive Substance Trade via Telegram during the COVID-19 Pandemic

2021 ◽  
pp. 1-6
Author(s):  
Matthijs Blankers ◽  
Daan van der Gouwe ◽  
Lavinia Stegemann ◽  
Laura Smit-Rigter
Keyword(s):  
Social Media ◽  
The Netherlands ◽  
Relative Increase ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide ◽  
Psychoactive Substance ◽  
Before And After ◽  
Other Substances

<b><i>Background:</i></b> In this article, we present an evaluation of online psychoactive substance trade via Telegram, a free encrypted social media messenger service. The evaluation took place during the COVID-19 pandemic, which allowed us to monitor the effects of the spring 2020 lockdown in the Netherlands on substance trade via Telegram. <b><i>Objective:</i></b> The objective of this study was to evaluate whether changes in psychoactive substance trade on Telegram markets in the Netherlands can be observed during the COVID-19 pandemic. <b><i>Results:</i></b> Between December 2, 2019, and June 29, 2020, a total of 70,226 posts appeared in two analyzed Telegram groups. A total of 5,643 posts were psychoactive substance related. Based on the analyzed posts, Telegram is mostly a ‘“sellers” market as only a minority of the posts (6.3%) could be identified as a request for a substance. The proportion of posts related to specific substances varied between the periods before, during, and after the lockdown. The proportion of posts on the stimulants ecstasy, cocaine, and amphetamine was lower during the lockdown than before and after. For psychedelics – ketamine, lysergic acid diethylamide (LSD), and 2,5-dimethoxy-4-bromophenethylamine (2C-B) – and other substances, there was a relative increase in the number of posts during the lockdown, which was maintained after the lockdown. <b><i>Conclusions:</i></b> Telegram analysis shows that in the Netherlands, online psychoactive substance trade may have been affected during the COVID-19 pandemic. The direction of this effect was different for different classes of substances.

Production of Tolerance to Psychosis-Producing Doses of Lysergic Acid Diethylamide

Science ◽  
1957 ◽  
Vol 126 (3281) ◽  
pp. 1020-1020 ◽  
Author(s):  
H. A. ABRAMSON ◽  
B. SKLAROFSKY ◽  
M. O. BARON ◽  
N. FREMONT-SMITH
Keyword(s):  
Lysergic Acid ◽  
Lysergic Acid Diethylamide

CLINICAL PHARMACOLOGY OF LYSERGIC ACID DIETHYLAMIDE

1997 ◽  
Vol 4 (5) ◽  
pp. 211 ◽  
Author(s):  
Kari Blaho ◽  
Kevin Merigian ◽  
Stephen Winbery ◽  
Stephen A. Geraci ◽  
Chantay Smartt
Keyword(s):  
Clinical Pharmacology ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide

Oral Sernyl in Obsessive States

1961 ◽  
Vol 107 (446) ◽  
pp. 109-114 ◽  
Author(s):  
Brian M. Davies
Keyword(s):  
Preliminary Report ◽  
Therapeutic Agent ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide ◽  
Psychological Disturbances ◽  
Synthetic Drug ◽  
Severe Disturbance

Sernyl, 1 aryl-cyclo-hexylamine, is a synthetic drug first used by the anaesthetists because, when given intravenously, it produces analgesia. However, the occurrence of psychological disturbances post-operatively led to the investigation of this drug by psychiatrists. It was found that Sernyl produces many interesting psychological disturbances, some of which resemble the primary symptoms of schizophrenia (Davies and Beech, 1960). In a previous paper (Davies, 1960) Sernyl was given intravenously to five patients with long-standing psychoneurotic illnesses. It proved to be an effective abreactive agent and produced some interesting results in three of the patients who had obsessional symptoms. Sernyl, in the doses used, is not an hallucinogen, though it produces other effects similar to lysergic acid diethylamide, which has been used extensively as a therapeutic agent, particularly in obsessional states (Sandison et al., 1954). The preliminary report suggested that Sernyl might have some practical advantages over LSD—in particular, it produced a less severe disturbance and its effects were over more quickly. Further investigations were clearly indicated and this present paper reports on the use of oral Sernyl in five patients with obsessional illnesses.

Characterisation of [3H]lysergic acid diethylamide binding to a 5-hydroxytryptamine receptor on human platelet membranes

1984 ◽  
Vol 97 (1-2) ◽  
pp. 87-93 ◽  
Author(s):  
David P. Geaney ◽  
Michael Schächter ◽  
J.Martin Elliot ◽  
David G. Grahame-Smith
Keyword(s):  
Human Platelet ◽  
Lysergic Acid ◽  
Lysergic Acid Diethylamide ◽  
Platelet Membranes
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