Eosinophilic/Allergic Colitis

Allergic colitis is a clinical manifestation of food allergy during the first months of life. It is estimated that genetic factors play a role in the expression of this allergic disease. This case report described the clinical progress of infants who were cousins from two distinct family groups with allergic colitis. Five infants under six months of age and of both sexes were studied, with a diagnosis of allergic colitis characterized clinically and histologically by (1) rectal bleeding; (2) exclusion of infectious causes of colitis; (3) disappearance of symptoms after elimination of cow's milk and dairy products from the child's and/or the mother's diet. Patients were submitted to the following diagnostic investigation: complete blood count; stool culture; parasitologic examination of stools; rectoscopy or colonoscopy; and rectal biopsy. Patient age varied from 40 days to six months; three were males. All patients presented with complaints of intense colic and rectal bleeding. The colonoscopy showed presence of hyperemia of the mucosa with microerosions and spontaneous bleeding upon the procedure. Microscopy revealed the existence of colitis with eosinophilia >20 e/HPF. Patients were treated with a hypoallergenic formula and showed remission of symptoms. After one year of age, all were submitted to an oral challenge with a milk formula and presented food tolerance. Allergic colitis is a disease with evident genetic inheritance and a temporary character.

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Fecal microbiota transplantation induces remission of infantile allergic colitis through gut microbiota re-establishment

World Journal of Gastroenterology ◽

10.3748/wjg.v23.i48.8570 ◽

2017 ◽

Vol 23 (48) ◽

pp. 8570-8581 ◽

Cited By ~ 14

Author(s):

Sheng-Xuan Liu ◽

Yin-Hu Li ◽

Wen-Kui Dai ◽

Xue-Song Li ◽

Chuang-Zhao Qiu ◽

...

Keyword(s):

Gut Microbiota ◽

Fecal Microbiota Transplantation ◽

Fecal Microbiota ◽

Allergic Colitis

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Dientamoeba fragilis Masquerading as Allergic Colitis

Journal of Pediatric Gastroenterology and Nutrition ◽

10.1097/00005176-199801000-00003 ◽

1998 ◽

Vol 26 (1) ◽

pp. 16-20 ◽

Cited By ~ 51

Author(s):

Carmello Cuffari ◽

Luc Oligny ◽

Ernest G. Seidman

Keyword(s):

Dientamoeba Fragilis ◽

Allergic Colitis

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P0545 KLEBSIELLA OXYTOCA(KO) INFECTION, A POSSSIBLE CAUSE OF COLITIS IN INFANTS PRESENTING WITH MILK INDUCED (???ALLERGIC???) COLITIS(MIC)

Journal of Pediatric Gastroenterology and Nutrition ◽

10.1097/00005176-200406001-00669 ◽

2004 ◽

Vol 39 (Supplement 1) ◽

pp. S263-S264

Author(s):

B. S. Bangaru ◽

P. M. Tierno

Keyword(s):

Klebsiella Oxytoca ◽

Allergic Colitis

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Serologic Investigations in Children with Inflammatory Bowel Disease and Food Allergy

Mediators of Inflammation ◽

10.1155/2009/512695 ◽

2009 ◽

Vol 2009 ◽

pp. 1-6 ◽

Cited By ~ 6

Author(s):

Urszula Grzybowska-Chlebowczyk ◽

Halina Woś ◽

Aleksander L. Sieroń ◽

Sabina Więcek ◽

Aleksandra Auguściak-Duma ◽

...

Keyword(s):

Inflammatory Bowel Disease ◽

Food Allergy ◽

Small Bowel ◽

Blood Serum ◽

Bowel Disease ◽

Older Age ◽

Elisa Method ◽

Allergic Colitis ◽

Inflammatory Bowel ◽

Frequent Localization

The aim of the study was the evaluation of frequency and titre of IgA ASCA and IgG ASCA and p-ANCA, c-ANCA in children with IBD and occurrence of ASCA antibodies in relation to coexistence of FA. Patients and methods. The study comprised 95 children at the ages of 2 to 18 years. The diagnosis of IBD was established on the basis of Porto criteria. Tests of blood serum were performed in all children: IgA and IgG ASCA, p-ANCA, c-ANCA using ELISA method. Results. IgE-dependent FA was found in 32.5% children with UC and in 21% with CD. We did not observe any relation between the occurrence of FA and the frequency and ASCA titre. p-ANCA were significantly more frequent in the group of children with UC. The occurrence of ASCA antibodies was observed in 73.7% of children with CD, 17.5% with UC and almost 30% with allergic colitis. Conclusions. Patients with CD and the presence of ASCA revealed a significantly more frequent localization of lesions within the small bowel and a tendency towards older age. We observed a connection between the occurrence of antibodies and the examined mutations of gene NOD2/CARD15.

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