Comparison of Interobserver Agreement and Diagnostic Accuracy for IASLC/ITMIG Thymic Epithelial Tumor Staging Among Co-registered FDG-PET/MRI, Whole-body MRI, Integrated FDG-PET/CT, and Conventional Imaging Examination with and without Contrast Media Administrations

Author(s):  
Yoshiharu Ohno ◽  
Yuji Kishida ◽  
Shinichiro Seki ◽  
Hisanobu Koyama ◽  
Masao Yui ◽  
...  
2014 ◽  
Vol 24 (5) ◽  
pp. 1153-1165 ◽  
Author(s):  
Annemieke S. Littooij ◽  
Thomas C. Kwee ◽  
Ignasi Barber ◽  
Claudio Granata ◽  
Malou A. Vermoolen ◽  
...  

2013 ◽  
Vol 38 (7) ◽  
pp. e290-e296 ◽  
Author(s):  
Andrei Iagaru ◽  
Phillip Young ◽  
Erik Mittra ◽  
David W. Dick ◽  
Robert Herfkens ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Alessandro Stecco ◽  
Francesco Buemi ◽  
Martina Quagliozzi ◽  
Mariangela Lombardi ◽  
Alberto Santagostino ◽  
...  

Background. The purpose of this study was to compare the accuracy of whole-body MRI with diffusion-weighted sequences (WB-DW-MRI) with that of18F-FDG-PET/CT in the staging of patients with primary gastrointestinal lymphoma.Methods. This retrospective study involved 17 untreated patients with primary abdominal gastrointestinal lymphoma. All patients underwent18F-FDG-PET/CT and WB-DW-MRI. Histopathology findings or at least 6 months of clinical and radiological follow-up was the gold standard. The Musshoff-modified Ann Arbor system was used for staging, and diagnostic accuracy was evaluated on a per-node basis.Results. WB-DW-MRI exhibited 100% sensitivity, 96.3% specificity, and 96.1% and 100% positive and negative predictive values (PPV and NPV), respectively. The sensitivity, specificity, and PPV and NPV of PET/CT were 95.9%, 100%, and 100% and 96.4%, respectively. There were no statistically significant differences between the two techniquesp=0.05. The weighted kappa agreement statistics with a 95% confidence interval were 0.97 (0.95–0.99) between the two MRI readers and 0.87 (0.82–0.92) between the two methods.Conclusions. WB-DW-MRI appears to have a comparable diagnostic value to18F-FDG-PET/CT in staging patients with gastrointestinal lymphoma.


2018 ◽  
Vol Volume 11 ◽  
pp. 3597-3608 ◽  
Author(s):  
Danyang Wang ◽  
Yanlei Huo ◽  
Suyun Chen ◽  
Hui Wang ◽  
Yingli Ding ◽  
...  

2019 ◽  
Vol 61 (2) ◽  
pp. 156-167
Author(s):  
Kim Sivesgaard ◽  
Lars P Larsen ◽  
Michael Sørensen ◽  
Stine Kramer ◽  
Sven Schlander ◽  
...  

Background Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) can detect extrahepatic disease before local treatment of colorectal liver metastases. Purpose To investigate if whole-body magnetic resonance imaging (MRI) added to gadoxetic acid liver MRI could replace FDG-PET/CT for detection of extrahepatic disease in patients with colorectal liver metastases eligible for hepatic local treatment. Material and Methods This health-research-ethics-committee-approved prospective consecutive diagnostic accuracy study with written informed consent analyzed 79 cases included between 29 June 2015 and 7 February 2017. Whole-body MRI covering the thorax, abdomen, and pelvis and FDG-PET/CT including contrast-enhanced CT was performed 0–3 days before local treatment of liver metastases. Whole-body MR images were read independently by two readers. FDG-PET/CT images were read independently by two pairs of readers. Histopathology and follow-up imaging were used as reference standard. Sensitivities and specificities were calculated and compared including noninferiority analysis. Results Seventy-five malignant lesions and 419 benign lesions were confirmed. Sensitivities of both PET/CT reader pairs 1 and 2 (56.7 and 67.9%) and MRI reader 2 (63.0%) were significantly higher than that of MRI reader 1 (42.7) (P<0.04). Specificities of both PET/CT reader pairs 1 and 2 (92.5 and 92.4%) and MRI reader 1 (91.1%) were significantly higher than that of MRI reader 2 (86.3%) ( P < 0.02). Sensitivity of MRI reader 2 was non-inferior compared to PET/CT reader pair 1. Specificities of both MRI readers were non-inferior to both PET/CT reader pairs. Conclusion For detection of extrahepatic disease in patients with colorectal liver metastases, whole-body MRI was non-inferior to FDG-PET/CT for some reader combinations. However, reader-independent non-inferiority could not be demonstrated.


2018 ◽  
Vol 36 (6) ◽  
pp. 382-393 ◽  
Author(s):  
Mohammad Abd Alkhalik Basha ◽  
Maged Abdel Gelil Hamed ◽  
Rania Refaat ◽  
Mohamad Zakarya AlAzzazy ◽  
Manar A. Bessar ◽  
...  

2016 ◽  
Vol 30 (4) ◽  
pp. 309-319 ◽  
Author(s):  
Hyo Sang Lee ◽  
Jungsu S. Oh ◽  
Young Soo Park ◽  
Se Jin Jang ◽  
Ik Soo Choi ◽  
...  

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