A Cell-free Biodegradable Synthetic Artificial Ligament for the Reconstruction of Anterior Cruciate Ligament in a Rat Model

Author(s):  
Yohei Kawakami ◽  
Kazuhiro Nonaka ◽  
Naomasa Fukase ◽  
Antonio D’ Amore ◽  
Yoichi Murata ◽  
...  
Author(s):  
Mark Stasiak ◽  
Peter Torzilli ◽  
Carl Imhauser ◽  
Jonathan Packer ◽  
Asheesh Bedi ◽  
...  

A novel system was developed to investigate the effect of mechanical load on tendon to bone healing, using a rat model of ACL reconstruction. A greater understanding of the effects of mechanical load may improve rehabilitation practices for the more than 100,000 ACL reconstructions each year in the US alone.[1] The purpose of this study was to assess: the accuracy of knee joint distraction, variability in fixator compliance, and ability of animals to tolerate the fixator over a typical loading protocol.


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