Clinical Features in Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome

2005 ◽  
Vol 140 (4) ◽  
pp. 637-641 ◽  
Author(s):  
Chiho Goda ◽  
Satoshi Kotake ◽  
Akira Ichiishi ◽  
Kenichi Namba ◽  
Nobuyoshi Kitaichi ◽  
...  
2020 ◽  
Vol 35 (12) ◽  
pp. 2269-2274
Author(s):  
Douglas J. Stewart ◽  
Thivya Sekar ◽  
Kjell Tullus

2020 ◽  
Vol 13 (2) ◽  
pp. e232077
Author(s):  
Robert BR Moreton ◽  
Brian W Fleck ◽  
Joyce Davidson ◽  
David Hughes

A 9-year-old girl presented to hospital with a 6-week history of non-specific constitutional symptoms and weight loss. She initially underwent extensive medical investigation without diagnosis being achieved. Although raised inflammatory markers and impaired renal function were noted during her initial admission to hospital, it was her subsequent presentation 2 weeks later with sudden-onset bilateral anterior uveitis that prompted a renal biopsy that indicated acute tubulointerstitial nephritis. A diagnosis of tubulointerstitial nephritis and uveitis (TINU) syndrome was made and systemic glucocorticoid treatment initiated to prevent visual loss and preserve renal function. She has subsequently been reviewed in multidisciplinary outpatient clinics and treated with a tapering regimen of immunosuppressive therapy. Her treatment has been complicated by the side effects of glucocorticoids and by persistent relapses in ocular disease and abnormalities on urinalysis. Recent clinical investigations indicate that her uveitis is controlled and that renal function remains well preserved.


2009 ◽  
Vol 13 (1) ◽  
pp. 73-76 ◽  
Author(s):  
Hisa Suzuki ◽  
Katsunobu Yoshioka ◽  
Masato Miyano ◽  
Isseki Maeda ◽  
Keiko Yamagami ◽  
...  

2016 ◽  
Vol 25 ◽  
Author(s):  
Şiyar Erdoğmuş ◽  
Serkan Aktürk ◽  
Zeynep Kendi Çelebi ◽  
Kenan Keven ◽  
Şule Şengül ◽  
...  

Author(s):  
Yukiko Kitamura ◽  
shohei kuraoka ◽  
Koji Nagano ◽  
hiroshi tamura

Distinguishing between late-onset TINU syndrome and drug-induced AIN remains difficult given that patients with TINU syndrome may develop uveitis long after the onset of AIN. Therefore, ophthalmic examination is required not only upon diagnosis but also continuously or when eye symptoms, and relapse of urinary findings are observed.


Author(s):  
Mariam P. Alexander ◽  
Ajay K. Singh

Parenchymal renal disease can be considered anatomically under the headings of glomerular, tubular, tubulointerstitial, and vascular disease. Most patients present with a clinical syndrome of nephron injury. The clinical features of parenchymal renal disease frequently depend on the component of the kidney that is affected—for example, glomerulonephritis presents with worsened kidney function, hypertension, hematuria, proteinuria, and red cell casts. Tubulointerstitial nephritis presents with azotemia, pyuria and/or white cell casts.


2015 ◽  
Vol 83 (2015) (02) ◽  
pp. 117-120 ◽  
Author(s):  
Shinsuke Fujita ◽  
Keisuke Sugimoto ◽  
Akane Izu ◽  
Tsukasa Takemura

Sign in / Sign up

Export Citation Format

Share Document