Delayed spontaneous closure of blue laser-induced full thickness macular hole

Herein, we report the longitudinal observation of a case with reopening of the macular hole associated with a lamellar macular hole-associated epiretinal proliferation (LHEP) followed by spontaneous closure in patients with stage 2 idiopathic macular hole. A 64-year-old woman was referred for the decreased visual acuity (VA) and acute anorthopia in the right eye. Funduscopy and optical coherence tomography (OCT) showed stage 2 full-thickness macular hole without posterior vitreous detachment (PVD) and operculum formation. Her best-corrected visual acuity (BCVA) was 20/32. One month later, the diameter of the macular hole was getting small and VA improved. Six months later, the macular hole was treated spontaneously with the attached hyaloid membrane to the macula by OCT and the BCVA improved to 20/20. Fourteen months after the first visit, the BCVA decreased to 20/50 and the patient was diagnosed with stage 4 macular hole with complete PVD. OCT showed full-thickness macular hole with a LHEP in the right eye. After 25G-gauge vitrectomy with the peeling of internal limiting membrane (ILM) and LHEP, the macular hole was closed and BCVA finally improved to 20/25. Spontaneous macular hole closure without PVD may rarely occur in patients with LHEP. The surgical removal of ILM and LHEP may contribute to the successful macular hole closure after vitrectomy.

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Spontaneous closure of a chronic full thickness macular hole after failed surgery

American Journal of Ophthalmology Case Reports ◽

10.1016/j.ajoc.2018.12.006 ◽

2019 ◽

Vol 13 ◽

pp. 59-61 ◽

Cited By ~ 2

Author(s):

Jennifer Lee ◽

Vincent Q. Nguyen ◽

Mallika K. Doss ◽

Andrew W. Eller

Keyword(s):

Macular Hole ◽

Spontaneous Closure ◽

Full Thickness ◽

Full Thickness Macular Hole ◽

Failed Surgery

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Characteristics and Risk Factors for Spontaneous Closure of Idiopathic Full-Thickness Macular Hole

Journal of Ophthalmology ◽

10.1155/2019/4793764 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6 ◽

Cited By ~ 5

Author(s):

Xida Liang ◽

Wu Liu

Keyword(s):

Risk Factors ◽

Macular Hole ◽

Case Reports ◽

Primary Treatment ◽

Small Sample ◽

Spontaneous Closure ◽

Full Thickness ◽

Macular Holes ◽

Pubmed Database ◽

Full Thickness Macular Hole

Idiopathic full-thickness macular hole is a severe visual impairment disease. Pars plana vitrectomy remains the primary treatment option for idiopathic full-thickness macular holes, and over 90% idiopathic full-thickness macular holes are closed by vitrectomy surgery. However, the full-thickness macular hole may close spontaneously, with a good visual acuity progress. Since recent studies are small-sample studies and case reports, the characteristics for spontaneous closure of idiopathic full-thickness macular holes are not fully understood. Here, we review the articles in PubMed database from 1999 to 2018 and discuss the characteristic and the risk factors, especially OCT structure features, for spontaneous closure of idiopathic full-thickness macular holes.

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Full thickness macular hole formation and spontaneous closure during intravitreal Ranibizumab therapy for central retinal vein occlusion

Retinal Cases & Brief Reports ◽

10.1097/icb.0000000000001074 ◽

2020 ◽

Vol Publish Ahead of Print ◽

Author(s):

Neha Goel

Keyword(s):

Macular Hole ◽

Central Retinal Vein Occlusion ◽

Spontaneous Closure ◽

Full Thickness ◽

Hole Formation ◽

Intravitreal Ranibizumab ◽

Vein Occlusion ◽

Full Thickness Macular Hole ◽

Macular Hole Formation ◽

Central Retinal Vein

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Spontaneous formation and closure of full thickness macular hole in a vitrecto-mised eye : a case report

Nepalese Journal of Ophthalmology ◽

10.3126/nepjoph.v9i2.19270 ◽

2018 ◽

Vol 9 (2) ◽

pp. 199-202

Author(s):

Rajya Laxmi Gurung

Keyword(s):

Case Report ◽

Macular Hole ◽

Male Patient ◽

Pars Plana Vitrectomy ◽

Spontaneous Closure ◽

Rare Entity ◽

Full Thickness ◽

Spontaneous Formation ◽

Full Thickness Macular Hole ◽

Pars Plana

The exact pathogenesis of macular hole (MH) is controversial with most of the cases being idiopathic. Trauma is an important cause of secondary MH formation. MH post Pars Plana Vitrectomy (PPV) is an even rare entity with only a handful of cases reported so far ( Kumagai et al, 2008; Smiddy W.E, 1993; Kimura et al, 2005). An even rarer event is spontaneous closure of post PPV full thickness macular hole (FTMH), though spontaneous closure of traumatic macular hole (TMH) has been reported before. Herein, we report a 26 year old male patient who developed FTMH post PPV that closed spontaneously.

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