AS-54: Sex as an Independent Risk Factor for Adverse Events following Carotid Stenting for Carotid Artery Stenosis: Acute and Long-Term Follow-Up Results

BackgroundCarotid artery stenting (CAS) for symptomatic carotid artery stenosis (SCS) has been proved to be safe and effective in many randomized controlled trials, but the safety and efficacy of CAS for asymptomatic carotid artery stenosis (ACS) is not clear.ObjectiveTo prospectively compare the outcomes of CAS between patients with ACS and SCS.Methods402 consecutive patients, 233 with ACS and 169 with SCS, underwent CAS. The primary outcome was a composite of death, stroke or myocardial infarction at 30 days and during the follow-up period. Procedural success and complications such as hyperperfusion, sinus-cardiac reflex, gastrointestinal hemorrhage, myocardial infarction, acute thrombosis, and vagus nerve reflex were also compared between the ACS and SCS groups.ResultsCAS was successful in all patients. There were no significant differences in baseline characteristics of the patients (age, gender, hypertension, diabetes, smoking, alcohol consumption and dyslipidemia) and in 30-day or long-term follow-up outcomes between the ACS and SCS groups.ConclusionsPeriprocedural and long-term follow-up outcomes of CAS appear similar for ACS and SCS.

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Endovascular treatment with angioplasty or stenting versus endarterectomy in patients with carotid artery stenosis in the Carotid And Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial

The Lancet Neurology ◽

10.1016/s1474-4422(09)70228-5 ◽

2009 ◽

Vol 8 (10) ◽

pp. 898-907 ◽

Cited By ~ 126

Author(s):

Jörg Ederle ◽

Leo H Bonati ◽

Joanna Dobson ◽

Roland L Featherstone ◽

Peter A Gaines ◽

...

Keyword(s):

Carotid Artery ◽

Endovascular Treatment ◽

Vertebral Artery ◽

Carotid Artery Stenosis ◽

Randomised Trial ◽

Transluminal Angioplasty ◽

Artery Stenosis ◽

Long Term Follow Up

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Impact of ventricular arrhythmias on survival in patients after myocardial infarction

International Journal of Diagnostic Imaging ◽

10.5430/ijdi.v1n1p21 ◽

2014 ◽

Vol 1 (1) ◽

pp. 21 ◽

Cited By ~ 1

Author(s):

Katarzyna Anna Mitręga ◽

Agnieszka Kolczyńska ◽

Joanna Hanzel ◽

Sylwia Cebula ◽

Stanisław Morawski ◽

...

Keyword(s):

Myocardial Infarction ◽

Risk Factor ◽

Ventricular Arrhythmias ◽

Independent Risk Factor ◽

Premature Ventricular Beats ◽

Large Numbers ◽

Ventricular Extrasystoles ◽

Long Term Follow Up

Introduction: Despite the continuous development of new methods of pharmacological and invasive treatment for patients with acute myocardial infarction (MI) the prognosis of long-term survival is still uncertain. Therefore, there is still need to look for new noninvasive predictors of death in patients after MI. Aim: To analyze the prognostic value of ventricular arrhythmias in predicting mortality following MI in long-term follow-up. Methods: We analyzed 390 consecutive patients (114 females and 276 males, aged 63.9 ± 11.15 years, mean EF: 43.8 ± 7.9%) with MI treated invasively. On the 5th day after MI 24-hour digital Holter recording was performed to assess the number of premature ventricular beats (VPB) and their sustained forms such as: salvos and nonsustained ventricular tachycardia (nsVT < 30 s). The large numbers of ventricular extrasystoles: ≥ 10 VPB / hour were considered as abnormal. In echocardiography the size of heart cavities and cardiac contractile function were evaluated. Within 30.1 ± 15.1 months of follow-up 38 patients died. Results: In the group of patients with MI the mean value of ventricular ectopy during the day was: 318.8 ± 1447.6. Large numbers of ventricular extrasystoles were observed in 75% patients, while nsVT in 6% patients. Significant differences in the incidence of death after MI were observed in patients with nsVT and ventricular salvos. In the group of patients who died in comparison to the group of patients who survived in long-term follow-up, a significantly less ventricular ectopic incidence was noted (9.83% vs 90.17%, p < 0.01). In patients who died after MI more premature ventricular beats (≥ 10 VPB / h) and a greater nsVT incidence were observed; however not significant. Moreover, in patients with MI the systolic and diastolic LV dimension, decreased values of hemoglobin, salvos and nsVT incidence are the independent risk factors of death. The strongest independent risk factor of death after MI is salvos (HR: 1.32, P < 0.01). Conclusions: In long term follow-up the largest differences in death were observed in patients with ventricular salvos and nsVT. Furthermore, ventricular salvos are the strongest independent risk factor of death in patients with AMI.

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