scholarly journals Treatment of Lassa virus infection in outbred guinea pigs with first-in-class human monoclonal antibodies

2016 ◽  
Vol 133 ◽  
pp. 218-222 ◽  
Author(s):  
Robert W. Cross ◽  
Chad E. Mire ◽  
Luis M. Branco ◽  
Joan B. Geisbert ◽  
Megan M. Rowland ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Virus Infection ◽  
Guinea Pigs ◽  
Lassa Virus ◽  
Human Monoclonal Antibodies

scholarly journals Human Monoclonal Antibodies as Adjuvant Treatment of Chronic Hepatitis B Virus Infection

2019 ◽  
Vol 10 ◽  
Author(s):  
Antonella Cerino ◽  
Stefania Mantovani ◽  
Dalila Mele ◽  
Barbara Oliviero ◽  
Stefania Varchetta ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Monoclonal Antibodies ◽  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Adjuvant Treatment ◽  
Hepatitis B Virus Infection ◽  
Human Monoclonal Antibodies ◽  
Chronic Hepatitis B Virus ◽  
B Virus

scholarly journals Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice

Cell Reports ◽  
2019 ◽  
Vol 26 (6) ◽  
pp. 1585-1597.e4 ◽  
Author(s):  
Vanessa Salazar ◽  
Brett W. Jagger ◽  
Juthathip Mongkolsapaya ◽  
Katherine E. Burgomaster ◽  
Wanwisa Dejnirattisai ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Virus Infection ◽  
Zika Virus ◽  
Human Monoclonal Antibodies

scholarly journals A recombinant vesicular stomatitis-based Lassa fever vaccine elicits rapid and long-term protection from lethal Lassa virus infection in guinea pigs

npj Vaccines ◽  
2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Derek R. Stein ◽  
Bryce M. Warner ◽  
Geoff Soule ◽  
Kevin Tierney ◽  
Kathy L. Frost ◽  
...  
Keyword(s):  
Virus Infection ◽  
Guinea Pigs ◽  
Lassa Fever ◽  
Lassa Virus ◽  
Vesicular Stomatitis

scholarly journals Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
James E. Robinson ◽  
Kathryn M. Hastie ◽  
Robert W. Cross ◽  
Rachael E. Yenni ◽  
Deborah H. Elliott ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Lassa Virus ◽  
Human Monoclonal Antibodies ◽  
Virus Glycoprotein

scholarly journals Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection

mBio ◽  
2021 ◽  
Author(s):  
Alex W. Wessel ◽  
Michael P. Doyle ◽  
Taylor B. Engdahl ◽  
Jessica Rodriguez ◽  
James E. Crowe ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
West Nile Virus ◽  
Virus Infection ◽  
Envelope Protein ◽  
West Nile Virus Infection ◽  
Therapeutic Antibodies ◽  
Ns1 Protein ◽  
Human Monoclonal Antibodies ◽  
West Nile ◽  
Paradoxical Worsening

Therapeutic antibodies against flaviviruses often promote neutralization by targeting the envelope protein of the virion. However, this approach is hindered by a possible concern for antibody-dependent enhancement of infection and paradoxical worsening of disease.

scholarly journals Cross-protective potential of anti-nucleoprotein human monoclonal antibodies against lethal influenza A virus infection

2016 ◽  
Vol 97 (9) ◽  
pp. 2104-2116 ◽  
Author(s):  
Yoshikazu Fujimoto ◽  
Yukiko Tomioka ◽  
Hiroki Takakuwa ◽  
Gen-Ichiro Uechi ◽  
Toshiyo Yabuta ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Virus Infection ◽  
Influenza A Virus ◽  
Influenza A ◽  
Human Monoclonal Antibodies ◽  
Protective Potential ◽  
Influenza A Virus Infection

scholarly journals Use of Human Monoclonal Antibodies to Treat Chikungunya Virus Infection

2012 ◽  
Vol 207 (2) ◽  
pp. 319-322 ◽  
Author(s):  
Jan Fric ◽  
Sébastien Bertin-Maghit ◽  
Cheng-I Wang ◽  
Alessandra Nardin ◽  
Lucile Warter
Keyword(s):  
Monoclonal Antibodies ◽  
Virus Infection ◽  
Chikungunya Virus ◽  
Human Monoclonal Antibodies
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