scholarly journals Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease

2020 ◽  
Vol 175 ◽  
pp. 104707 ◽  
Author(s):  
Jun Ping Quek ◽  
Shuang Liu ◽  
Zhenzhen Zhang ◽  
Yan Li ◽  
Elizabeth Yihui Ng ◽  
...  
Keyword(s):  
Small Molecule ◽  
Structural Characterization ◽  
Zika Virus ◽  
Ns3 Protease

scholarly journals Structural characterization of the linked NS2B-NS3 protease of Zika virus

FEBS Letters ◽  
2017 ◽  
Vol 591 (15) ◽  
pp. 2338-2347 ◽  
Author(s):  
Yan Li ◽  
Wint Wint Phoo ◽  
Ying Ru Loh ◽  
Zhenzhen Zhang ◽  
Elizabeth Yihui Ng ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Zika Virus ◽  
Ns3 Protease

scholarly journals Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists

2017 ◽  
Vol 143 ◽  
pp. 218-229 ◽  
Author(s):  
Sergey A. Shiryaev ◽  
Chen Farhy ◽  
Antonella Pinto ◽  
Chun-Teng Huang ◽  
Nicole Simonetti ◽  
...  
Keyword(s):  
Small Molecule ◽  
Zika Virus ◽  
Two Component ◽  
Ns3 Protease

scholarly journals Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor

Structure ◽  
2018 ◽  
Vol 26 (4) ◽  
pp. 555-564.e3 ◽  
Author(s):  
Yan Li ◽  
Zhenzhen Zhang ◽  
Wint Wint Phoo ◽  
Ying Ru Loh ◽  
Rong Li ◽  
...  
Keyword(s):  
Small Molecule ◽  
Zika Virus ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor ◽  
Ns3 Protease ◽  
Structural Insights

scholarly journals Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor

2018 ◽  
Vol 24 (31) ◽  
pp. 7861-7865 ◽  
Author(s):  
Franziska Kappert ◽  
Sridhar Sreeramulu ◽  
Hendrik R. A. Jonker ◽  
Christian Richter ◽  
Vladimir V. Rogov ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Small Molecule ◽  
Structural Characterization ◽  
Fibroblast Growth Factor Receptor ◽  
Growth Factor Receptor ◽  
Fibroblast Growth ◽  
Allosteric Inhibitor

scholarly journals Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Rafael M. Couñago ◽  
Charles K. Allerston ◽  
Pavel Savitsky ◽  
Hatylas Azevedo ◽  
Paulo H. Godoi ◽  
...  
Keyword(s):  
Small Molecule ◽  
Structural Characterization ◽  
Small Molecule Inhibitors ◽  
Loop Conformations
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