Treatment With Botulinum Toxin Improves Upper-Extremity Function Post Stroke: A Systematic Review and Meta-Analysis

2013 ◽  
Vol 94 (5) ◽  
pp. 977-989 ◽  
Author(s):  
Norine Foley ◽  
Shelialah Pereira ◽  
Katherine Salter ◽  
Manuel Murie Fernandez ◽  
Mark Speechley ◽  
...  
2016 ◽  
Vol 64 (2) ◽  
pp. 91-112 ◽  
Author(s):  
David Pérez-Cruzado ◽  
Jose Antonio Merchán-Baeza ◽  
Manuel González-Sánchez ◽  
Antonio I. Cuesta-Vargas

Cureus ◽  
2021 ◽  
Author(s):  
Mohammad Nasb ◽  
Sayed Zulfiqar Ali Shah ◽  
Hong Chen ◽  
Ahmed S Youssef ◽  
Zhenlan Li ◽  
...  

2006 ◽  
Vol 86 (10) ◽  
pp. 1387-1397 ◽  
Author(s):  
Shu-Fen Sun ◽  
Chien-Wei Hsu ◽  
Chiao-Wen Hwang ◽  
Pei-Te Hsu ◽  
Jue-Long Wang ◽  
...  

Abstract Background and Purpose. Constraint-induced movement therapy (CIMT) is a promising intervention for retraining upper-extremity function after a stroke. The purpose of this case report is to describe the use of a combination of botulinum toxin type A (BtxA) and a modified CIMT program for a patient with severe spasticity who was unable to use his right upper extremity. Case Description. The 52-year-old patient, who had a stroke 4 years ago, did not meet the minimum motor criteria for CIMT benefit. After receiving BtxA injections targeting the elbow, wrist, and finger flexors, he completed a 4-week program of modified CIMT followed by a 5-month home exercise program. Outcomes. The patient exhibited improvement in muscle tone (the velocity-dependent resistance to stretch that muscle exhibits) and in scores on several upper-extremity function tests (Modified Ashworth Scale, Motor Activity Log, Wolf Motor Function Test, Action Research Arm Test, and Fugl-Meyer Assessment of Motor Recovery). He also reported making much progress in the functional use of the involved upper extremity. Discussion. In a patient with severe flexor spasticity and nonuse of the dominant upper extremity after a stroke, a combined treatment of BtxA and modified CIMT may have resulted in improved upper-extremity use.


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