Chitosan hydrogel containing amelogenin-derived peptide: Inhibition of cariogenic bacteria and promotion of remineralization of initial caries lesions

2019 ◽  
Vol 100 ◽  
pp. 42-48 ◽  
Author(s):  
Qian Ren ◽  
Longjiang Ding ◽  
Zhongcheng Li ◽  
Xiuqing Wang ◽  
Kun Wang ◽  
...  
2018 ◽  
Vol 5 (2) ◽  
pp. 69-76 ◽  
Author(s):  
Qian Ren ◽  
Zhongcheng Li ◽  
Longjiang Ding ◽  
Xiuqing Wang ◽  
Yumei Niu ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (6) ◽  
pp. e0234122
Author(s):  
Patrícia de Carvalho ◽  
Marcelo Bönecker ◽  
Gustavo Tello ◽  
Jenny Abanto ◽  
Luciana Butini Oliveira ◽  
...  

BDJ ◽  
2012 ◽  
Vol 213 (11) ◽  
pp. 551-557 ◽  
Author(s):  
A. Guerrieri ◽  
C. Gaucher ◽  
E. Bonte ◽  
J. J. Lasfargues

2011 ◽  
Vol 58 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Tatjana Savic-Stankovic ◽  
Milica Jovanovic-Medojevic ◽  
Slavoljub Zivkovic

Introduction. Dental status of most people with special needs is not satisfactory. Many of them are edentulous or toothless, with acute extensive caries lesions present, high DMFT index and severe periodontal disease. The objective of this study was to examine the dental status of mentally impaired persons who live in the special institution ?Srce u jabuci? in Pancevo. Material and Methods. Clinical examination was performed on 114 institutionalized patients (68 male and 46 female), age 22 to 71 years. Patients were divided in two groups; the first group consisted of 71 persons who had a moderate mental disorder (F71), while the second group included 43 respondents with severe mental retardation (F72). Oral examination revealed: the number of present teeth, caries lesions, the presence of restorations, the number of extracted teeth, the presence of residual roots, fractures and the presence and number of fixed restorations. Results. The mean DMFT of total examined teeth was 20.33?7.63. The greatest percentage found for extracted teeth (63.76%): in the first group 63.23%, and in the second 64.06%. The percentage of teeth that had caries lesions of all examined teeth was 33.48%, while the lowest percentage was for restored teeth (2.76%). In majority of examined people, initial caries, deep caries, or tooth with the exposed pulp (K1 - 51.74% K2 - 40.35%, K3 - 51.75%) were not found. A high percentage of examined people had more than 10 extracted teeth (52.63%). Most of them did not have any restoration in the mouth (81%) and only three persons had fixed denture. Conclusion. Dental status of institutionalized mentally impaired persons showed high prevalence of extracted teeth, significant presence of carious lesions and small percentage of restored teeth with inadequate oral hygiene.


2006 ◽  
Vol 53 (4) ◽  
pp. 229-235 ◽  
Author(s):  
Nikola Stojanovic ◽  
Jelena Krunic

Caries is the most frequent oral disease in all age groups. Aim: The aim of this study was to determine dental status and caries prevalence in adolescents in the Eastern Bosnian region, in Foca municipality Materials and methods: The study comprised 300 pupils of secondary schools, of both sexes and aged between 15 and 18 in Foca municipality. Dental check-up was conducted by a single dentist using daylight, dental mirror and dental probe. Caries prevalence was analyzed using the DMFT index. Results: Results showed that the dominant components of DMFT were filled (51.7%) and decayed teeth (36.8%) while extracted teeth were least frequent (11.8). Initial caries was observed most frequently in upper (48%) and lower (39.7%) molars and least frequently in lower anterior teeth (8.4%). Deep caries lesions were most often found in upper (35,7%) and lower (33.3%) molars and rarely in lower anterior teeth (3.3%). Conclusion: Adolescents in Eastern Bosnia (Foca municipality) have great number of carious and unrestored teeth and, therefore, the implementation of primary dental healthcare system is necessary as well as looking for a solution to this problem.


Author(s):  
V. Melnik ◽  
L. Gorzov ◽  
S. Melnik ◽  
Ya. Duganchik

Introduction. The largest amount of information about the dental caries is provided by the International Caries Detection and Assessment II system (ICDAS II), which is known as evidence-based approach to clinical visual detection of dental caries and enables to detect the stage and depth of carious lesions from the slightest changes in dental enamel to visible cavities affecting dentin. This system has been developed by the group of leading experts in the field of cariology. The results obtained by determining the ICDAS II index contribute to making right clinical decision in the choice of prevention and treatment methods, as well as to predicting the carious progression. The aim of the study is to assess the prevalence and intensity of initial dental caries in people using the ICDAS II index. Materials and methods. A total of 32 patients aged 12 to 25 years were examined. During the dental examination, we assessed the prevalence of dental caries using the ICDAS II. Clinical findings were recorded in oral follow-up charts proposed by the ICDAS Foundation for Epidemiological Studies, which allow us to record dental hard tissue status using six codes: three for assessing carious changes in enamel and three for assessing carious changes in dentine in a sequence of growing severity. Statistical processing of the findings was performed using Student's t-test. Results. Carious lesions were detected in all study participants, their total number was 285, of which 140 (49.1%) had the code 1 and 145 (50.8%) had the code 2 according to the ICDAS II. On average, each of the participants had 9.28 ± 0.67 foci of enamel demineralization. The average number of lesions with codes 1 and 2 by the ICDAS II was respectively 4.54 ± 0.51 and 4.74 ± 0.38 (p> 0.05). The average intensity of dental caries increased with age from 8.29 ± 0.83 in 12-15 year old individuals to 9.39 ± 1.20 in 18-25 year old individuals (p> 0.05), mainly by the growth of the average number of the mean number of caries lesions with the code 1 according to the ICDAS II. Mostly carious lesions are found on the masticatory surfaces, their total number made up 159 (55.7%). 101 (35.4%) caries lesions were found on the vestibular and oral parts of the tooth surfaces, and 25 (8.9%) average lesions were detected on the proximal surfaces. The average intensity of caries detected on the chewing surfaces of the teeth was 5.15 ± 0.49 and was significantly higher than on the vestibular and oral (3.33 ± 0.57, p <0.05) and proximal (0.79 ± 0, 20, p <0.001) surfaces. Conclusion. The obtained results showed a high intensity of carious lesions, with their predominance in the active stages in the two age groups under the study. This proves the appropriateness of using diagnostic ICDAS criteria for early detection of initial caries and its proper treatment.


2009 ◽  
Vol 79 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Otmar Kronenberg ◽  
Adrian Lussi ◽  
Sabine Ruf

Abstract Objective: To test the null hypotheses: (1) there is no difference in the caries protective effect of ozone and Cervitec/Fluor Protector during multibracket (MB) appliance therapy, and (2) DIAGNOdent and quantitative light-induced fluorescence (QLF) are not superior to a visual evaluation of initial caries lesions. Materials and Methods: Twenty right-handed patients with a very poor oral hygiene who required full MB appliance therapy were analyzed during 26 months. In a split-mouth-design, the four quadrants of each patient were either treated with ozone, a combination of Cervitec and Fluor Protector, or served as untreated controls. The visible plaque index (VPI) and white spot formation were analyzed clinically. DIAGNOdent and QLF were used for a quantitative assessment of white spot formation. Results: The average VPI in all four dental arch quadrants amounted to 55.6% and was independent of the preventive measure undertaken. In the quadrants treated with Cervitec/Fluor Protector, only 0.7% of the areas developed new, clinically visible white spots. This was significantly (P &lt; .05) less than in the quadrants treated with ozone (3.2%). The lesions detected with QLF only partially corresponded to the clinically detected white spots, while DIAGNOdent proved to be unable to detect any changes at all. Conclusions: The caries protective effect of Cervitec/Fluor Protector during MB therapy was superior to ozone, and a visual evaluation of initial caries lesions was superior to both DIAGNOdent and QLF.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Teija Raivisto ◽  
AnnaMaria Heikkinen ◽  
Leena Kovanen ◽  
Hellevi Ruokonen ◽  
Kaisa Kettunen ◽  
...  

Background. Dental caries is the most common infection in the world and is influenced by genetic and environmental factors. Environmental factors are largely known, but the role of genetic factors is quite unknown. The aim was to investigate the genetic background of caries in Finnish adolescents. Materials and Methods. This study was carried out at the Kotka Health Center in Eastern Finland. 94 participants aged 15–17 years gave approval for the saliva and DNA analyses. However, one was excluded in DNA analysis; thus, the overall number of participants in analysis was 93. Caries status was recorded clinically and from bite-wing X-rays to all 94 participants. Genomic DNA was extracted by genomic QIAamp® DNA Blood Mini Kit and genotyped for polymorphisms. The results were analyzed using additive and logistic regression models. Results. No significant associations between caries and the genes studied were found. However, SNPs in DDX39B and MPO showed association tendencies but were not statistically significant after false discovery rate (FDR) analysis. SNPs in VDR, LTA, and MMP3 were not statistically significant with initial caries lesions after FDR analysis. Conclusion. The present study could not demonstrate statistically significant associations between caries and the genes studied. Further studies with larger populations are needed.


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