Paper 61: The Origin of the Repaired Tissues for Full-thickness Articular Cartilage Defects Using Bone-marrow-derived Mesenchymal Cells of the Transgenic Rat

2012 ◽  
Vol 28 (8) ◽  
pp. e104-e105
Keyword(s):  
Bone Marrow ◽  
Articular Cartilage ◽  
Mesenchymal Cells ◽  
Cartilage Defects ◽  
Transgenic Rat ◽  
Full Thickness ◽  
Articular Cartilage Defects

In-advance trans-medullary stimulation of bone marrow enhances spontaneous repair of full-thickness articular cartilage defects in rabbits

2010 ◽  
Vol 341 (3) ◽  
pp. 371-379 ◽  
Author(s):  
Kazuya Nishizawa ◽  
Shinji Imai ◽  
Tomohiro Mimura ◽  
Mitsuhiko Kubo ◽  
Susumu Araki ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Articular Cartilage ◽  
Cartilage Defects ◽  
Full Thickness ◽  
Articular Cartilage Defects ◽  
Spontaneous Repair ◽  
Stimulation Of

scholarly journals Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow

Rheumatology ◽  
2004 ◽  
Vol 43 (8) ◽  
pp. 980-985 ◽  
Author(s):  
R. Katayama ◽  
S. Wakitani ◽  
N. Tsumaki ◽  
Y. Morita ◽  
I. Matsushita ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Articular Cartilage ◽  
Mesenchymal Cells ◽  
Cartilage Defects ◽  
Articular Cartilage Defects

scholarly journals Autologous Costal Cartilage Graft—A New Method to Treat Articular Cartilage Defects: Case Report and Note of Surgical Technique

Joints ◽  
2018 ◽  
Vol 06 (04) ◽  
pp. 246-250
Author(s):  
Antonio Gigante ◽  
Marco Cianforlini ◽  
Luca Farinelli ◽  
Riccardo Girotto ◽  
Alberto Aquili
Keyword(s):  
Articular Cartilage ◽  
Femoral Condyle ◽  
Costal Cartilage ◽  
Donor Site ◽  
Standard Technique ◽  
Cartilage Defects ◽  
Cartilage Graft ◽  
Full Thickness ◽  
Articular Cartilage Defects ◽  
Costal Cartilage Graft

AbstractFull-thickness articular cartilage defects do not heal spontaneously. Several techniques have been developed to address this issue, but none resulted in the restitutio ad integrum of the articular cartilage. The most frequent sites of chondral lesion in the knee are medial femoral condyle and patella. The patellofemoral lesions are characterized by outcomes that are generally worse than those of tibiofemoral ones. To date, it has been well recognized the chondrogenic potential of rib perichondrium, and costal cartilage grafts have been extensively used in reconstructive surgery. Considering the need to find a gold standard technique to restore articular defect, we developed and here described a new technique to repair cartilage lesions of the knee using autologous costal cartilage graft with its perichondrium. This innovative surgical approach can be used to treat full thickness articular defects using autologous hyaline cartilage, making it possible to cover wide defects. This one step technique is low invasive, not technically demanding with minimal donor site morbidity and it has low costs. The long-term clinical efficacy of the method remains to be evaluated.

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