scholarly journals The impact of older age on long term survival in living donor liver transplantation: A propensity score matching analysis

Author(s):  
Ali Avanaz ◽  
Volkan Doğru ◽  
Abdullah Kisaoglu ◽  
Vural Taner Yilmaz ◽  
Demet Sarıdemir Ünal ◽  
...  
Surgery ◽  
2016 ◽  
Vol 160 (1) ◽  
pp. 251-252
Author(s):  
Long-Bin Jeng ◽  
Ashok Thorat ◽  
Horng-Ren Yang ◽  
Chun-Chieh Yeh ◽  
Te-Hung Chen ◽  
...  

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243873
Author(s):  
Sumin Chae ◽  
Junghee Choi ◽  
Sujin Lim ◽  
Ho Joong Choi ◽  
Jaesik Park ◽  
...  

Background We investigated the impact of postreperfusion syndrome (PRS) on hyperglycemia occurrence and connecting (C) peptide release, which acts as a surrogate marker for insulin resistance, during the intraoperative period after graft reperfusion in patients undergoing living donor liver transplantation (LDLT) using propensity score (PS)-matching analysis. Patients and methods Medical records from 324 adult patients who underwent elective LDLT were retrospectively reviewed, and their data were analyzed according to PRS occurrence (PRS vs. non-PRS groups) using the PS-matching method. Intraoperative levels of blood glucose and C-peptide were measured through the arterial or venous line at each surgical phase. Hyperglycemia was defined as a peak glucose level >200 mg/dL, and normal plasma concentrations of C-peptide in the fasting state were taken to range between 0.5 and 2.0 ng/mL. Results After PS matching, there were no significant differences in pre- and intra-operative recipient findings and donor-graft findings between groups. Although glucose and C-peptide levels continuously increased through the surgical phases in both groups, glucose and C-peptide levels during the neohepatic phase were significantly higher in the PRS group than in the non-PRS group, and larger changes in levels were observed between the preanhepatic and neohepatic phases. There were higher incidences of C-peptide levels >2.0 ng/mL and peak glucose levels >200 mg/dL in the neohepatic phase in patients with PRS than in those without. PRS adjusted for PS with or without exogenous insulin infusion was significantly associated with hyperglycemia occurrence during the neohepatic phase. Conclusions Elucidating the association between PRS and hyperglycemia occurrence will help with establishing a standard protocol for intraoperative glycemic control in patients undergoing LDLT.


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