An Unusual Case of Giant Mediastinal Teratoma With Malignant Transformation

2008 ◽  
Vol 86 (1) ◽  
pp. 302-304 ◽  
Author(s):  
Chang Chen ◽  
Hui Zheng ◽  
Sen Jiang
2006 ◽  
Vol 11 (5) ◽  
pp. 213-217
Author(s):  
Delia P??rez Montiel ◽  
Hugo Dom??nguez Malag??n

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Arunee Dechaphunkul ◽  
Gilbert Bigras ◽  
Michael Sawyer

Germ cell tumor with somatic malignant transformation is an uncommon phenomenon occurring about 7% of all mediastinal teratomas. Among all transformed component, sarcoma appears to be the most frequent histology, followed by primitive neuroectodermal tumor (PNET) and adenocarcinoma. To our knowledge, there were 3 cases of colonic-type adenocarcinoma arising in a primary teratoma have been reported to date. However, none of them received chemotherapy directed to transformed histology given localized disease at presentation. We, therefore, report here the first case of patient who achieved good response from chemotherapy directed to transformed histology, which confirms the importance of chemotherapy regimen used.


1995 ◽  
Vol 21 (8) ◽  
pp. 731-734 ◽  
Author(s):  
ARLENE J. HERZBERG ◽  
ROSALIE ELENITSAS ◽  
CYNTHIA R. STROHMEYER

2010 ◽  
Vol 29 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Douglas Barker ◽  
Rohini Sharma ◽  
Angus McIndoe ◽  
Ed Blair ◽  
Marcia Hall ◽  
...  

2005 ◽  
Vol 102 (2) ◽  
pp. 376-381 ◽  
Author(s):  
Stephan Saikali ◽  
Anne Le Strat ◽  
Anne Heckly ◽  
Nathalie Stock ◽  
Jean-Marie Scarabin ◽  
...  

✓ The authors report an unusual case of multicentric pleomorphic xanthoastrocytoma (PXA) in a 36-year-old woman with neurofibromatosis Type 1 (NF1). Both lesions were diagnosed as PXA but demonstrated different neuroimaging features and very different outcomes. Although the occipital lesion was cured surgically, the cerebellar tumor recurred three times and underwent malignant transformation into an anaplastic oligodendroglioma. The authors discuss the causes of PXA and suggest that it could originate from common bipotential precursor cells with two phenotypes.


2007 ◽  
Vol 46 (8) ◽  
pp. 1200-1201 ◽  
Author(s):  
Ignacio Duran ◽  
Luis Riveros ◽  
Dominik R. Berthold ◽  
Joan Sweet ◽  
Malcolm J. Moore

2013 ◽  
Vol 28 (3) ◽  
pp. 476 ◽  
Author(s):  
Young-Joon Ryu ◽  
Su Hyun Yoo ◽  
Min Jung Jung ◽  
Sejin Jang ◽  
Kyung-Ja Cho

Author(s):  
Gao Fengming

Transmission electron microscope(TEM) and scanning electron microscope(SEM) were widely used in experimental tumor studies. They are useful for evaluation of cellular transformation in vitro, classification of histological types of tumors and treating effect of tumors. We have obtained some results as follows:1. Studies on the malignant transformation of mammalian cells in vitro. Syrian golden hamster embryo cells(SGHEC) were transformed in vitro by ThO2 and/or ore dust. In a few days after dust added into medium, some dust crystals were phagocytized. Two weeks later, malignant transformation took place. These cells were of different size, nuclear pleomorphism, numerous ribosomes, increasing of microvilli on cell surface with various length and thickness, and blebs and ruffles(Figs. 1,2). Myelomonocytic leukemic transformation of mouse embryo cells(MEC) was induced in vitro by 3H-TdR. Transformed cells were become round from fusiform. The number of mitochondria and endoplasmic reticulum was reduced, ribosomes and nucleoli increased, shape of nuclei irregular, microvilli increased, and blebs and ruffles appeared(Fig. 3).


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