Naturally Occurring Mediastinal Teratoma with Malignant Transformation in an Adult Male

Retrorectal cystic hamartomas or tailgut cysts are infrequent congenital lesions presenting as presacral masses originating from the embryonic hindgut. They are commonly diagnosed in middle-aged women. Physicians must have a high index of suspicion to diagnose this rare tumor. We report a case of retrorectal hamartoma in a 70-year-old male presenting as rectal bleeding instead of the usual compressive symptoms. The utility of imaging modalities and the paramount importance of histopathology has been described. The treatment modality is surgical excision to prevent the potential malignant transformation.

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Teratoma with Naturally Occurring Malignant Transformation in a Child

Annals of Thoracic and Cardiovascular Surgery ◽

10.5761/atcs.cr.11.01658 ◽

2011 ◽

Vol 17 (6) ◽

pp. 588-590 ◽

Cited By ~ 7

Author(s):

Mamoru Takahashi ◽

Norihito Okumura ◽

Tomoaki Matsuoka ◽

Akihiko Yamashina ◽

Jun Nakano ◽

...

Keyword(s):

Malignant Transformation ◽

Naturally Occurring

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Serrated adenoma of stomach: A premalignancy?

Asian Journal of Oncology ◽

10.4103/2454-6798.173408 ◽

2015 ◽

Vol 01 (02) ◽

pp. 112-114

Author(s):

Divya Ail ◽

Hemamaheswari Kumar ◽

Geetha Prakash ◽

Preethi Selva ◽

J. Nagalakshmi

Keyword(s):

Young Adult ◽

High Risk ◽

Malignant Transformation ◽

Adult Male ◽

Immunohistochemical Staining ◽

The Elderly ◽

Serrated Adenoma ◽

Ki 67 ◽

Very High

ABSTRACTSerrated adenoma is a newly described entity in the group of gastric adenomas. Until date only 20 cases of gastric serrated adenoma have been reported. It is an important entity to be diagnosed accurately as it has a very high-risk of malignant transformation, especially those located in the cardia of stomach. Serrated adenoma associated with adenocarcinoma is more frequent in the elderly, but pure serrated adenoma is common in the young, in whom follow-up is mandatory. Gastric serrated adenoma has distinct location, definite histomorphology and characteristic Ki-67 immunohistochemical staining. Ki-67 staining helps to differentiated pure serrated adenoma from those associated with adenocarcinoma. We present a young adult male, incidentally detected to have gastric serrated adenoma.

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Response to 5-Fluorouracil-Based Chemotherapy in a Patient with Metastatic Colonic-Type Adenocarcinoma Arising in a Primary Mediastinal Teratoma

Case Reports in Oncological Medicine ◽

10.1155/2012/729278 ◽

2012 ◽

Vol 2012 ◽

pp. 1-4

Author(s):

Arunee Dechaphunkul ◽

Gilbert Bigras ◽

Michael Sawyer

Keyword(s):

Germ Cell ◽

Malignant Transformation ◽

Germ Cell Tumor ◽

Primitive Neuroectodermal Tumor ◽

Chemotherapy Regimen ◽

Cell Tumor ◽

Neuroectodermal Tumor ◽

Mediastinal Teratoma ◽

First Case ◽

Localized Disease

Germ cell tumor with somatic malignant transformation is an uncommon phenomenon occurring about 7% of all mediastinal teratomas. Among all transformed component, sarcoma appears to be the most frequent histology, followed by primitive neuroectodermal tumor (PNET) and adenocarcinoma. To our knowledge, there were 3 cases of colonic-type adenocarcinoma arising in a primary teratoma have been reported to date. However, none of them received chemotherapy directed to transformed histology given localized disease at presentation. We, therefore, report here the first case of patient who achieved good response from chemotherapy directed to transformed histology, which confirms the importance of chemotherapy regimen used.

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An Unusual Case of Giant Mediastinal Teratoma With Malignant Transformation

The Annals of Thoracic Surgery ◽

10.1016/j.athoracsur.2007.07.087 ◽

2008 ◽

Vol 86 (1) ◽

pp. 302-304 ◽

Cited By ~ 7

Author(s):

Chang Chen ◽

Hui Zheng ◽

Sen Jiang

Keyword(s):

Malignant Transformation ◽

Unusual Case ◽

Mediastinal Teratoma

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GENETIC CORRELATION BETWEEN RESISTANCE TO SWEETPOTATO WEEVIL AND OTHER INSECTS

HortScience ◽

10.21273/hortsci.29.7.727e ◽

1994 ◽

Vol 29 (7) ◽

pp. 727e-727

Author(s):

Paul G. Thompson ◽

J. C. Schneider ◽

Boyett Graves ◽

B. K. Kim

Keyword(s):

Genetic Correlation ◽

Adult Male ◽

Storage Root ◽

Male And Female ◽

Sweetpotato Weevil ◽

Naturally Occurring ◽

Environmental Interactions

Twenty-four half-sib sweetpotato families were field tested for freedom from injury by sweetpotato weevil and other soil inhabiting, injurious insects (WDS). Three pairs of adult male and female weevils were applied to the crown of each plant at the beginning of storage root enlargement. Naturally occurring numbers of WDS were high enough for considerable injury from those insects. WDS injury free roots ranged from 19% in Centennial, the suceptible control, to 57% in Regal, the resistant control. The highest family mean for percent non-injured by WDS was 55%. Weevil injury free roots ranged from 67% in Centennial to 90% in Regal with 3 families producing mean weevil non-injured roots of 89%. The genetic correlation between weevil injury free and WDS injury free roots was 0.69 ± 0.28. That estimate is preliminary and based on data from one environment. Evaluations will be repeated in 1994 for estimates of GXE to derive genetic correlation estimates with less environmental interactions.

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