Role of S114 in the NADH-induced conformational change and catalysis of 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni

Yi-Hsun Chang; Tzu-Jung Huang; Lea-Yea Chuang; Chi-Ching Hwang

doi:10.1016/j.bbapap.2009.06.006

Role of S114 in the NADH-induced conformational change and catalysis of 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ◽

10.1016/j.bbapap.2009.06.006 ◽

2009 ◽

Vol 1794 (10) ◽

pp. 1459-1466 ◽

Cited By ~ 4

Author(s):

Yi-Hsun Chang ◽

Tzu-Jung Huang ◽

Lea-Yea Chuang ◽

Chi-Ching Hwang

Keyword(s):

Conformational Change ◽

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni

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Role of Lys159 in the Proton Relay System of the 3α‐hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni

The FASEB Journal ◽

10.1096/fasebj.21.5.a273-d ◽

2007 ◽

Vol 21 (5) ◽

Author(s):

Chi‐Ching Hwang ◽

Yi‐Hsun Chang

Keyword(s):

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Relay System ◽

Proton Relay

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Understanding oligomerization in 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: An in silico approach and evidence for an active protein

Journal of Biotechnology ◽

10.1016/j.jbiotec.2006.11.024 ◽

2007 ◽

Vol 129 (1) ◽

pp. 131-139 ◽

Cited By ~ 11

Author(s):

Frank Hoffmann ◽

Christoph Sotriffer ◽

Andreas Evers ◽

Guangming Xiong ◽

Edmund Maser

Keyword(s):

In Silico ◽

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Active Protein

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Regulation of 3α-hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni: function and relationship of two operators

Chemico-Biological Interactions ◽

10.1016/s0009-2797(02)00251-x ◽

2003 ◽

Vol 143-144 ◽

pp. 411-423 ◽

Cited By ~ 4

Author(s):

Guangming Xiong ◽

Stefannie Markowetz ◽

Edmund Maser

Keyword(s):

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Relationship Of

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Characterization of a 3alpha-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from the Gram-Negative Bacterium Comamonas testosteroni

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1996.00744.x ◽

1996 ◽

Vol 241 (3) ◽

pp. 744-749 ◽

Cited By ~ 55

Author(s):

Udo C. T. Oppermann ◽

Edmund Maser

Keyword(s):

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Negative Bacterium ◽

Gram Negative

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Mechanism of Proton Transfer in the 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni

Journal of Biological Chemistry ◽

10.1074/jbc.m706336200 ◽

2007 ◽

Vol 282 (47) ◽

pp. 34306-34314 ◽

Cited By ~ 19

Author(s):

Yi-Hsun Chang ◽

Lea-Yea Chuang ◽

Chi-Ching Hwang

Keyword(s):

Proton Transfer ◽

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni

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Functional Expression, Purification, and Characterization of 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.2000.2813 ◽

2000 ◽

Vol 272 (2) ◽

pp. 622-628 ◽

Cited By ~ 32

Author(s):

Edmund Maser ◽

Eric Möbus ◽

Guangming Xiong

Keyword(s):

Hydroxysteroid Dehydrogenase ◽

Functional Expression ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Purification And Characterization

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Cloning and Sequencing of a New Comamonas Testosteroni Gene Encoding 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase

Advances in Experimental Medicine and Biology - Enzymology and Molecular Biology of Carbonyl Metabolism 7 ◽

10.1007/978-1-4615-4735-8_49 ◽

1999 ◽

pp. 395-402 ◽

Cited By ~ 8

Author(s):

Eric Möbus ◽

Edmund Maser

Keyword(s):

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Cloning And Sequencing ◽

Gene Encoding

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The Catalytic Roles of P185 and T188 and Substrate-Binding Loop Flexibility in 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni

PLoS ONE ◽

10.1371/journal.pone.0063594 ◽

2013 ◽

Vol 8 (5) ◽

pp. e63594 ◽

Cited By ~ 3

Author(s):

Chi-Ching Hwang ◽

Yi-Hsun Chang ◽

Hwei-Jen Lee ◽

Tzu-Pin Wang ◽

Yu-Mei Su ◽

...

Keyword(s):

Substrate Binding ◽

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Loop Flexibility ◽

Binding Loop

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A model on the regulation of 3α-hydroxysteroid dehydrogenase/carbonyl reductase expression in Comamonas testosteroni

Chemico-Biological Interactions ◽

10.1016/s0009-2797(00)00303-3 ◽

2001 ◽

Vol 130-132 ◽

pp. 723-736 ◽

Cited By ~ 10

Author(s):

Guangming Xiong ◽

Hans-Jörg Martin ◽

Andreas Blum ◽

Christina Schäfers ◽

Edmund Maser

Keyword(s):

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni

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Characterization and recombinant expression of the translational repressor RepB of 3α-hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni

Chemico-Biological Interactions ◽

10.1016/s0009-2797(02)00252-1 ◽

2003 ◽

Vol 143-144 ◽

pp. 425-433 ◽

Cited By ~ 8

Author(s):

Guangming Xiong ◽

Hans-Jörg Martin ◽

Edmund Maser

Keyword(s):

Recombinant Expression ◽

Hydroxysteroid Dehydrogenase ◽

Carbonyl Reductase ◽

Comamonas Testosteroni ◽

Translational Repressor

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